ABRAHAMS
S, SAMODIEN S, LILLY M, JOUBERT E, GELDERBLOM WCA. Differential
Modulation of Gene Expression Encoding Hepatic and Renal Xenobiotic
Metabolizing Enzymes by an Aspalathin-Enriched Rooibos Extract and
Aspalathin. PLANTA MEDICA 2019; 85:6-13.
AFZAN
A, BRÉANT L, BELLSTEDT DU, GRANT JR, QUEIROZ EF, WOLFENDER J-L,
KISSLING J. Can biochemical phenotype, obtained from herbarium samples,
help taxonomic decisions? – A case study using Gentianaceae. TAXON 2019; 68(4):771-782.
ALBERTS
JF, SCHATZMAYR G, MOLL W-D, DAVIDS I, RHEEDER JP, BURGER H-M, SHEPHARD
GS, GELDERBLOM WCA. Detoxification of the Fumonisin Mycotoxins in Maize:
An Enzymatic Approach. Toxins 2019; 11:art no. 523, 15 pages.
BADENHORST
M, BARRY CJ, SWANEPOEL CJ, VAN STADEN CT, WISSING J, ROHWER JM.
Workflow for Data Analysis in Experimental and Computational Systems
Biology: Using Python as 'Glue'. Processes 2019; 7:art. no. 460, 17 pages.
CLOETE
WJ, HAYWARD S, SWART P, KLUMPERMAN L. Degradation of proteins and
starch by combined immobilization of protease, alpha-amylase and
beta-galactosidase on a single electrospun nanofibrous membrane. Molecules 2019; 24(3):508: 9.
DE
JAGER C, ANECK-HAHN N, VAN ZIJL MC, HAYWARD S, SWART P, GENTHE B.
Endocrine disrupting chemicals in commercially available cling film
brands in South Africa. Human and Ecological Risk Assessment (HERA) 2019; 25(6):1633-1644.
DOMINGO
RW, VAN DER WESTHUYZEN R, HAMANN AR, MOSTERT KJ, BARNARD L, PAQUET T,
TJHIN ET, SALIBA KJ, VAN OTTERLO WAL, STRAUSS E. Overcoming synthetic
challenges in targeting coenzyme A biosynthesis with the antimicrobial
natural product CJ-15,801. MedChemComm 2019; 10:2118-2125.
DREYER J, RAUTENBACH M, BOOYSEN E, VAN STADEN ADP, DEANE SM, DICKS LMT. Xenorhabdus khoisanae SB10 produces Lys-rich PAX lipopeptides and a Xenocoumacin in its antimicrobial complex. BMC MICROBIOLOGY 2019; 19(1):art no. 132, 11 pages.
GENT
R, DU TOIT T, BLOEM LM, SWART AC. The 11β-hydroxysteroid dehydrogenase
isoforms: pivotal catalytic activities yield potent C11-oxy C19 steroids with 11βHSD2 favouring 11-ketotestosterone, 11-ketoandrostenedione and 11-ketoprogesterone biosynthesis. Journal of Steroid Biochemistry and Molecular Biology 2019; 189:116-126.
GENT
R, DU TOIT T, SWART AC. 11α-Hydroxyprogesterone, a potent
11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by
steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to
produce C11α-derivatives of 21-deoxycortisol and
11-hydroxyandrostenedione in vitro. Journal of Steroid Biochemistry and Molecular Biology 2019; 191:105369. 11 pages.
GUSTAVSSON
A-K, BANAEIYAN AA, VAN NIEKERK DD, SNOEP JL, ADIELS CB, GOKSÖR M.
Studying Glycolytic Oscillations in Individual Yeast Cells by Combining
Fluorescence Microscopy with Microfluidics and Optical Tweezers. Current Protocols in Cell Biology 2019; 82(1):e70, 26 pages.
HAFERKAMP
P, TJADEN B, SHEN L, BRÄSEN C, KOURIL T, SIEBERS B. The Carbon Switch
at the Level of Pyruvate and Phosphoenolpyruvate in Sulfolobus solfataricus P2. Frontiers in Microbiology 2019; 10:art. no. 757, 13 pages.
JOUBERT
E, DE BEER D, MALHERBE CJ, MULLER M, LOUW A, GELDERBLOM WCA. Formal
honeybush tea industry reaches 20 year milestone- progress of product
research targeting phenolic composition, quality and bioactivity. South African Journal of Botany 2019; 127:58-79.
JUHL
DW, VAN RENSBURG W, BOSSIS X, VOSLOO JA, RAUTENBACH M, BECHINGER B.
Tyrocidine A interactions with saccharides investigated by CD and NMR
spectroscopies. JOURNAL OF PEPTIDE SCIENCE 2019; 25(5):e3163, 11 Pages.
LE
MAITRE NC, PIRIE MD, BELLSTEDT DU. An approach to determining
anthocyanin synthesis enzyme gene expression in an evolutionary context:
an example from Erica plukenetii. Annals of Botany 2019; 124:121-129.
LE MAITRE NC, PIRIE MD, BELLSTEDT DU. Floral Color, Anthocyanin Synthesis Gene Expression and Control in Cape Erica Species. Frontiers in Plant Science 2019; 10:e1565, 9 pages.
LOOS B, KLIONSKY DJ, DU TOIT A, HOFMEYR JS. On the relevance of precision autophagy flux control in vivo - Points of departure for clinical translation. Autophagy 2019; 2019:13 pages.
LOUW A. GR Dimerization and the Impact of GR Dimerization on GR Protein Stability and Half-Life. Frontiers in Immunology 2019; 10:e1693, 15 pages.
NAGHILOO S, BELLSTEDT DU, CLABEN-BOCKHOFF R. The plasticity of breeding system in arid-adapted Zygophylloideae. JOURNAL OF ARID ENVIRONMENTS 2019; 162:1-9.
NEAL
ML, KÖNIG M, NICKERSON D, MISIRLI G, KALBASI R, DRÄGER A, ATALAG K,
CHELLIAH V, COOLING MT, COOK DL, CROOK S, DE ALBA M, FRIEDMAN SH, GARNY
A, GENNARI H, GLEESON P, GOLEBIEWSKI M, HUCKA M, JUTY N, MYERS C,
OLIVIER BG, SAURO HM, SCHARM M, SNOEP JL, ET. Harmonizing semantic
annotations for computational models in biology. BRIEFINGS IN BIOINFORMATICS 2019; 20(2):540-550.
OAKES
JA, LI N, WISTOW BRC, GRIFFIN A, BARNARD L, STORBECK K, CUNLIFFE VT,
KRONE NP. Ferredoxin 1b Deficiency Leads to Testis Disorganization,
Impaired Spermatogenesis, and Feminization in Zebrafish. Endocrinology 2019; 160(10):2401-2416.
PERKINS MS, LOUW-DU TOIT R, AFRICANDER DJ. Hormone therapy and breast cancer: emerging steroid receptor mechanisms. JOURNAL OF MOLECULAR ENDOCRINOLOGY 2019; 61(4):R133-R160.
PIRIE
MD, KANDZIORA M, NÜRK NM, LE MAITRE NC, MUGRABI DE KUPPLER AL, GEHRKE
B, OLIVER EGH, BELLSTEDT DU. Leaps and bounds: geographical and
ecological distance constrained the colonisation of the Afrotemperate by
Erica. BMC Evolutionary Biology 2019; 19:art. no. 222, 12 pages.
RÉGNIER
M, POLIZZI A, LUKOWICZ C, SMATI S, LASSERRE F, LIPPI Y, NAYLIES C,
LAFFITTE J, BÉTOULIÈRES C, MONTAGNER A, DUCHEIX S, GOURBEYRE P,
ELLERO-SIMATOS S, GELDERBLOM WCA, ET AL. The protective role of liver X
receptor (LXR) during fumonisin B1-induced hepatotoxicity. ARCHIVES OF TOXICOLOGY 2019; 93:505-517.
SAASA
V, BEUKES M, LEMMER Y, MWAKIKUNGA B. Blood Ketone Bodies and Breath
Acetone Analysis and their Correlations in Type 2 Diabetes Mellitus. Diagnostics 2019; 9(4):art no: 224, 10 pages.
SCHIFFER
L, BARNARD L, BARANOWSKI ES, GILLIGAN L, TAYLOR AE, ARLT W, SHACKLETON
CHL, STORBECK K. Human steroid biosynthesis, metabolism and excretion
are differentially reflected by serum and urine steroid metabolomes: A
comprehensive review. Journal of Steroid Biochemistry and Molecular Biology 2019; 194:art. no. 105439, 25 pages.
SHEPHARD
GS, BURGER H-M, RHEEDER JP, ALBERTS JF, GELDERBLOM WCA. The
effectiveness of regulatory maximum levels for fumonisin mycotoxins in
commercial and subsistence maize crops in South Africa. Food Control 2019; 97:77-80.
SKOSANA
SB, WOODLAND JG, CARTWRIGHT M, ENFIELD K, KOMANE M, LOUW-DU TOIT R, VAN
DER SPUY ZM, AVENANT C, AFRICANDER DJ, STORBECK K, HAPGOOD JP.
Differential metabolism of clinically-relevant progestogens in cell
lines and tissue: Implications for biological mechanisms. Journal of Steroid Biochemistry and Molecular Biology 2019; 189:145-153.
STANDER
MA, REDELINGHUYS H, MASIKE K, LONG H, VAN WYK B-E. Patterns of
Variation and Chemosystematic Significance of Phenolic Compounds in the
Genus Cyclopia (Fabaceae, Podalyrieae). Molecules 2019; 24:2352, 20 pages.
STEYN
HM, VON STADEN L, BELLSTEDT DU, VAN DER MERWE PDW, VAN WYK AE. Notes on
the phytogeography and conservation status of the genus Acanthopsis (Acantheae, Acanthaceae). Phytotaxa 2019; 415(4):157-178.
STORBECK
K, SCHIFFER L, BARANOWSKI ES, CHORTIS V, PRETE A, BARNARD L, GILLIGAN
L, TAYLOR AE, IDKOWIAK J, ARLT W, SHACKLETON CHL. Steroid Metabolome
Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism. ENDOCRINE REVIEWS 2019; 40(6):1605-1625.
SWART AC, JOHANNES ID, SATHYAPALAN T, ATKIN SL. The Effect of Soy Isoflavones on Steroid Metabolism. Frontiers in Endocrinology 2019; 10:art. no. 229, 10 Pages.
VAN
NIEKERK DD, GUSTAVSSON A-K, MOJICA-BENAVIDES M, ADIELS CB, GOKSÖR M,
SNOEP JL. Phosphofructokinase controls the acetaldehyde-induced phase
shift in isolated yeast glycolytic oscillators. BIOCHEMICAL JOURNAL 2019; 476:353-363.
VOLKE
DC, ROHWER JM, FISCHER R, JENNEWEIN S. Investigation of the
methylerythritol 4‑phosphate pathway for microbial terpenoid production
through metabolic control analysis. Microbial Cell Factories 2019; 18:e192, 15 pages.
VOSLOO
JA, SNOEP JL, RAUTENBACH M. Modelling the variable incorporation of
aromatic amino acids in the tyrocidines and analogous cyclodecapeptides.
Journal of Applied Microbiology 2019; 127:1665-1676.
WIUM
M, JONKER HI, OLIVIER A, BELLSTEDT DU, BOTES A. DNA vaccines against
Mycoplasma elicit humoral immune responses in ostriches. Frontiers in Immunology 2019; 10:art. no. 1061, 9 pages.
Hoofstukke in Boeke
STANFORD
NJ, SCHARM M, DOBSON PD, GOLEBIEWSKI M, HUCKA M, KOTHAMACHU VB,
NICKERSON D, OWEN S, PAHLE J, WITTIG U, WALTEMATH D, GOBLE C, MENDES P,
SNOEP JL. Data Management in Computational Systems Biology: Exploring
Standards, Tools, Databases, and Packaging Best Practices. In: Oliver
SG, Castilla JC (eds.)
Yeast Systems Biology. Methods in Molecular Bilogy, vol 2049, Humana, New York, USA, 2019: 285-314.
Doktorale voltooi
BALCOMB BH. The Staphylococcus aureus redoxome: Characterization of enzymes involved in oxidative stress resistance and survival. PhD, 2019. 214 pp. Promotor: STRAUSS E.
DU TOIT A. Measuring and Modelling Autophagic Flux. PhD, 2019. 232 pp. Promotor: LOOS B. Medepromotor: HOFMEYR JS.
JANA C. Synthesis, profiling and mode of action studies of PanSulfAms as inhibitors of coenzyme A biosynthesis and utilization. PhD, 2019. 182 pp. Promotor: STRAUSS E. Medepromotor: DE VILLIERS M.
Meesters voltooi
BRINK D. Investigating
progestin-mediated crosstalk between the androgen receptor and estrogen
receptor subtypes in breast cancer cell lines. MSc, 2019. 136 pp. Studieleier: AFRICANDER DJ.
EKSTEEN A. Investigating the role of inflammation, progestins and steroid receptors in breast cancer. MSc, 2019. 118 pp. Studieleier: AFRICANDER DJ. Medestudieleier: VERHOOG NJD.
HORN S. A Comparative Analysis of Within-host Models of Malaria Infection with Immune Response. MSc, 2019. 121 pp. Studieleier: VAN NIEKERK DD. Medestudieleier: SNOEP JL.
MAMHENDE PGM. Investigation of the antifungal activity of tryptophan-rich cyclic peptides. MSc, 2019. 162 pp. Studieleier: RAUTENBACH M.
MUIYSER SM. The role of PFK in the oscillatory yeast strain x2180. MSc, 2019. 93 pp. Studieleier: VAN NIEKERK DD. Medestudieleier: SNOEP JL.
ODENDAAL JCW. Glycolytic Flux Control of Glyceraldehyde 3-Phosphate Dehydrogenase in Yeast. MSc, 2019. 154 pp. Studieleier: SNOEP JL. Medestudieleier: VAN NIEKERK DD.
VAN WYK M. The eect of adenylate kinase on the glycolytic oscillations of Saccharomyces cerevisiae. MSc, 2019. 86 pp. Studieleier: SNOEP JL. Medestudieleier: VAN NIEKERK DD, KOURIL T.
VAN WYK RJ. Development of cyclodecapeptides from the tyrothricin complex as anticancer peptides. MSc, 2019. 174 pp. Studieleier: RAUTENBACH M.