​​​​​​Department of Paediatrics and Child Health


Dr Sandi Holgate

After completing internship and a further year of work in Pietermaritzburg, KZN, Dr Holgate worked in the United Kingdom and then Australia for 4 years.  She started her first year of Paediatric training in Brisbane, Australia.  She subsequently completed her Paediatric training at Red Cross Hospital and the University of Cape Town.  She then specialised further in neonatology at Groote Schuur Hospital.  She has been employed as a neonatologist at Tygerberg Hospital since 2006.

Dr Holgate is a member of the United South African Neonatal Association where she has been treasurer since 2016.


Published Articles:

1st Author:

Holgate SL, Rabie H, Smith P, Cotton MF. Trough Lopinavir Concentrations in Preterm HIV-infected Infants  Pediatr Infect Dis J. 2012 Jun;31(6):602-4 

Holgate SL, Bekker A, Rabie H, Cotton MF.  Oseltamivir Use in Low-Birth Weight Infants During the 2009 nH1N1 Influenza A Outbreak in the Western Cape, South Africa. J Trop Pediatr. 2012 Apr;58(2):102-6. Epub 2011 Jun 7 


Horn AR, Pieper C, Els I, Holgate SL.  Early Surfactant Therapy and Nasal Continuous Positive Airways Pressure for Mild Respiratory Distress Syndrome – a Pilot Study.  SAJCH July 2009 Vol 3 No 2: 48 – 54 

Kirsten GF, Kirsten CL, Henning PA, Smith J, Holgate SL, Bekker A, Kali GT, Harvey J.  The Outcome of ELBW Infants Treatedwith NCPAP and InSurE in a Resource-Limited Institution.  Pediatrics. 2012 Apr;129(4):e952-9. Epub 2012 Mar 19 

De Waal R, Kroon SM, Holgate SL, Horn AR, Tooke JL, Normal J, et al.  Nevirapine concentrations in preterm and low birth weight HIV exposed infants: implications for dosing recommendations.  Pediatr Infect Dis J. 2014 Dec;33(12): 1231-3 

Maritz J, van Zyl G, Mellors JW, Theron GB, Nachega JB, Rabie H, Holgate SL, Preiser W, Bester M, Cotton MF.  Feasibility of a targeted, very early infant HIR diagnosis algorithm in a resource-limited setting.  International Journal of Infectious Diseases.  April 2014, Vol 21, Supplement 1, Page 129 

Cotton MF, Holgate S, Nelson A, Rabie H, Wedderburn C, Mirochnick M.  The last and first frontier – emerging challenges for HIV treatment and prevention in the first week of life with emphasis on premature and low birth weight infants.  J Int AIDS Soc 2015 Dec 2; 18(7 Suppl 6) 

Frigati L, Wynberg E, Maritz JS, Holgate SL, Cotton MF, Rabie H.  Antiretroviral treatment Initiated in the first month of life.  Pediatr. Infect Dis J, 2017 June; 36(6): 584-587. 

Dramowski A, Lloyd LG, Bekker A, Holgate S, Reddy K, Aucamp M, Finlayson H.  Neonatal listeriosis during a countrywide epidemic: a tertiary hospital's experience.  S Afr Med J 2018;108(10):818-827 

Oppel KB, Holgate SL, Finlayson H. A retrospective review of Listeria Monocytogenes infection at Tygerberg Children's Hospital, Cape Town, South Africa, from 2006 to 2016: Is empirical ampicillin still indicated after the first month of life? A Afr Med J 2018; 108(11) 937-943