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Division of Radiobiology
Conference contributions
Conference contributions since 2012
Manunu B, Serafin A, Akudugu J: Evaluation of Radiation-Induced Changes in the Expression of Bcl2, Parp1, PI3K, Hsp90 Pathway-Related Genes in Cancer Lines. Keystone Symposia, São Paulo, Brazil, 19-23 November 2019 (oral).
Akudugu J. The MultiRad Platform as a Handy Tool for High Throughput Radiobiological Research. International Congress of Radiation Research (ICRR), Manchester, UK, 25 – 29 August 2019 (invited talk).
Maleka S, Serafin A, Akudugu J. Concomitant targeting of PI3K, mTOR and AR exhibits strong synergism in human prostate cell lines. SAAPMB Congress, Cape Town, South Africa, October 2019 (oral).
Hamid MB, Serafin AM, Akudugu JM. Changes in metabolic activity of cancer and normal cell lines after X-ray irradiation and inhibitor treatment. SAAPMB Congress, Cape Town, South Africa, October 2019 (oral).
Chinhengo A, Serafin A, Akudugu JM. Radiofrequency field exposure enhances
in vitro
cellular radiosensitivity. SAAPMB Congress, Cape Town, South Africa, October 2019 (oral).
Manunu B, Serafin A, Akudugu J. Evaluation of Radiation-Induced Changes in the Expression of Bcl
2,
Parp-1, PI3K, Hsp90 Pathway-Related Genes in Cancer Cell Lines. SAAPMB Congress, Cape Town, South Africa, October 2019 (oral).
Guillaume MM, Serafin A, Akudugu J. Inhibition of PARP-1 by ABT888 can potentially cause reduction in colony size of lung cancer cells. SAAPMB Congress, Cape Town, South Africa, October 2019 (oral).
Chinhengo A, Serafin A, Akudugu JM. Radiofrequency waves preferentially enhance
in vitro
cellular radiosensitivity to large fractional doses. 63
rd
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2019 (oral).
Hamid MB, Serafin AM, Akudugu JM. Changes in metabolic activity of cancer and normal cells after X-ray irradiation and inhibitor treatment. 63
rd
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2019 (oral).
Chinhengo A, Serafin A, Akudugu JM. Effects of low and intermediate electromagnetic waves on radiosensitivity of normal and cancer cells
in vitro
. 62
nd
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2018 (oral).
Serafin A, Akudugu JA, Bohm L, Fernandez P, Aziz N, van der Merve A, Chinhengo A, Achel D. Urokinase plasminogen activator and plasminogen activator inhibitor type-1 as clinical markers for prostate cancer. CANSA Congress, University of Pretoria, South Africa, July 2018 (oral).
Serafin A, Chinhengo A, Fernandez P, Akudugu JM. Urokinase Plasminogen Activator (uPA) and Plasminogen Activator Inhibitor type-1 (PAI-1) as clinical markers for prostate cancer. 62
nd
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2018 (oral).
Milambo JPM, Kotze MJ, Erasmus RT, Akudugu JM. The impact of medically supervised exercise interventions on treatment-induced adverse effects in postmenopausal breast cancer patients: Systematic review and meta-analysis. 62
nd
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2018 (oral).
Hamid MB, Serafin AM, Akudugu JM. Evaluating the metabolic activity of cancer and normal cells after X-ray irradiation and inhibitor treatment. 62
nd
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2018 (oral).
Chinhengo A, Serafin A, Akudugu JM. Evaluation of cellular sensitivity to a split radiation dose and a combination of a single radiation dose and electromagnetic field exposure. SAAPMB Congress, Durban, South Africa, September 2017 (oral).
Johnson CP, Trauernicht CJ, Serafin AM, Akudugu JM. Measurement on an X-ray irradiator. SAAPMB Congress, Durban, South Africa, September 2017 (poster).
Maleka S, Serafin AM, Akudugu JM. A comparison of the effectiveness of targeted therapy and radiotherapy in human prostate cell lines. SAAPMB Congress, Durban, South Africa, September 2017 (oral).
Hamid MB, Serafin AM, Akudugu JM. Evaluation of the biological effectiveness of X-ray irradiation and epidermal growth factor receptor inhibition. SAAPMB Congress, Durban, South Africa, September 2017 (oral).
Chinhengo A, Serafin A, Akudugu JM. Evaluation of cellular sensitivity to a split radiation dose and a combination of a single radiation dose and electromagnetic field exposure. 61
st
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2017 (oral).
Pupwe G, Fourie AE, Akudugu J. A retrospective analysis of toxicity and outcomes following chemotherapy for the older population at a single institution. 61
st
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2017 (poster).
Johnson CP, Trauernicht CJ, Serafin AM, Akudugu JM. Measurement on an X-ray irradiator. 61
st
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2017 (poster).
Thebe TT, Fourie AE, Akudugu J. The prevalence of
Helicobacter pylori
infection in patients with gastric cancer at a single institution. 61
st
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2017 (poster).
Maleka S, Serafin AM, Akudugu JM. A comparison of the effectiveness of targeted therapy and radiotherapy in human prostate cell lines. 61
st
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2017 (oral).
Hamid MB, Serafin AM, Akudugu JM. Evaluation of the biological effectiveness of X-ray irradiation and epidermal growth factor receptor inhibition. 61
st
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2017 (oral).
Chinhengo A, Serafin A, Akudugu JM. Evaluation of cellular sensitivity to a split radiation dose and a combination of a single radiation dose and electromagnetic field exposure. 18
th
SASMO/SASCRO Congress, Johannesburg, South Africa, August 2017 (oral).
Pupwe G, Fourie AE, Akudugu J. A retrospective analysis of toxicity and outcomes following chemotherapy for the older population at a single institution. 18
th
SASMO/SASCRO Congress, Johannesburg, South Africa, August2017 (poster).
Johnson CP, Trauernicht CJ, Serafin AM, Akudugu JM. Measurement on an X-ray irradiator. 18
th
SASMO/SASCRO Congress, Johannesburg, South Africa, August 2017 (poster).
Maleka S, Serafin AM, Akudugu JM. A comparison of the effectiveness of targeted therapy and radiotherapy in human prostate cell lines. 18
th
SASMO/SASCRO Congress, Johannesburg, South Africa, August 2017 (oral).
Hamid MB, Serafin AM, Akudugu JM. Evaluation of the biological effectiveness of X-ray irradiation and epidermal growth factor receptor inhibition. 18
th
SASMO/SASCRO Congress, Johannesburg, South Africa, August 2017 (oral).
Thebe TT, Fourie AE, Akudugu J. The prevalence of
Helicobacter pylori
infection in patients with gastric cancer at a single institution. 18
th
SASMO/SASCRO Congress, Johannesburg, South Africa, August 2017 (poster).
Vawda Z, Akudugu JM, Pitcher RD, Groenewald W. Diagnostic reference levels for paediatric computed tomography. 60
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2016 (oral).
Begg W, Fourie AE, Akudugu JM. Short-course radiotherapy with delayed surgery: an attractive option for the treatment of locally advanced rectal carcinoma in a resource-limited setting. 60
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2016 (oral).
Maleka S, Serafin AM, Akudugu JM. Evaluation of cytotoxicity of BEZ-235 and AG-1478 in prostate cancer cells. 60
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2016 (oral).
Hamid MB, Serafin AM, Akudugu JM. EGFR targeting in triple negative breast cancer. 60
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2016 (oral).
Chinhengo A, Serafin A, Hamman B, Akudugu J. Electromagnetic fields induce frequency-dependent radioprotection and radiosensitization in in vitro cell cultures. 60
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2016 (oral).
Lombe DC, Jeremic B, Akudugu J, Sinske S, McCaul M. Sub-site study of salivary gland malignancies treated with neutron radiotherapy provides better information for patient selection. ASCO Annual Meeting, Chicago, Illinois, USA, June 2016 (oral).
Hamman B, Serafin A, Sewram V, Akudugu J. Radiomodifying effects of medicinal plants on pancreatic cancer cells. 14
th
International Congress of the International Radiation Protection Association, Cape Town, South Africa, May 2016 (poster).
Chinhengo A, Serafin A, Akudugu J. Evaluation of the effect of low and intermediate frequency electromagnetic waves on radiosensitivity. 14
th
International Congress of the International Radiation Protection Association, Cape Town, South Africa, May 2016 (poster).
Achel DG, Achoribo E, Agbenyegah S, Adaboro RM, Donkor S, Adu Bobi NNA-K, Agyekum AA, Akoamoa F, Tagoe SN, Kyei KA, Yarnney J, Serafin A, Akudugu JM. Establishing capacity for biological dosimetry at Ghana Atomic Energy Commission. 3rd (final) Research Coordination Meeting (RCM), IAEA Headquarters, VIC, Vienna, Austria, March 2016.
Vawda Z, Groenewald WA, Pitcher RD, Akudugu JM. Diagnostic reference levels for emergency head CT in paediatric patients. European Congress of Radiology Conference, Vienna, Austria, March 2016 (oral).
Lombe DC, Sinske SM, Akudugu JM. Treatment of parotid gland malignancies with neutron radiotherapy – Tygerberg experience. AORTIC 2015 - 10
th
International Conference on Cancer in Africa, Marrakech, Morocco, November 2015 (poster).
Kemp FW, Portugal F, Akudugu JM, Neti PVSV, Azzam EI, Ferraris RP, Howell RW. Effect of a diet enriched with vitamins A, C, and E on absorption of Po-210 in intestines. 61st Radiation Research Meeting, Weston, Florida, USA, September 2015 (poster).
Hamunyela RH, Serafin AM, Hamid MB, Maleka S, Achel DG, Akudugu JM. Radiosensitization of human breast cancer cells with a cocktail of specific inhibitors of HER-2, PI3K, and mTOR. 61
st
Radiation Research Meeting, Weston, Florida, USA, September 2015 (poster).
Hamid MB, Serafin AM, Hamunyela RH, Maleka S, Achel DG Akudugu JM. Radiosensitisation of low HER-2 expressing human breast cancer cell lines. 17
th
SASMO/SASCRO Congress, Cape Town, South Africa, August 2015 (poster).
Hamunyela RH, Serafin AM, Hamid MB, Maleka S, Achel DG, Akudugu JM. Radiosensitisation of human breast cancer cells with specific inhibitors of HER-2, PI3K, and mTOR. 17
th
SASMO/SASCRO Congress, Cape Town, South Africa, August 2015 (poster).
Maleka S, Serafin A, Akudugu J. The specific inhibitor of PI3K and mTOR (BEZ-235) has potential radio-protective effect. 17
th
SASMO/SASCRO Congress, Cape Town, South Africa, August 2015 (oral).
Lombe DC, Sinske SM, Akudugu JM. Treatment of parotid gland malignancies with neutron radiotherapy – Tygerberg experience. 17
th
SASMO/SASCRO Congress, Cape Town, South Africa, August 2015 (poster).
Hamman B, Serafin A, Sewram V, Akudugu J. Radiomodifying effects of medicinal plants on pancreatic cancer cells. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Begg W, Fourie AE, Akudugu JM. Short course radiotherapy with delayed surgery - an attractive option for the treatment of locally advanced rectal carcinoma in a resource limited setting. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Achel DG, Serafin A, Morkel M, Akudugu J. Protein biomarkers for biological dosimetry. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Lombe DC, Sinske SM, Akudugu JM. Treatment of parotid gland malignancies with neutron radiotherapy – Tygerberg experience. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Hamid MB, Serafin AM, Akudugu JM. Novel treatment strategies for cancers of the breast, cervix and lung. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Hamunyela R, Serafin A, Akudugu J. A cocktail of specific inhibitors of HER-2, PI3K, and mTOR radiosensitises human breast cancer cells. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Maleka S, Serafin A, Akudugu J. The specific inhibitor of PI3K and mTOR (BEZ-235) has potential radio-protective effect. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Chinhengo A, Serafin A, Akudugu J. Evaluation of the effect of low and intermediate frequency electromagnetic waves on radiosensitivity. 59
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2015 (oral).
Maleka S, Hamunyela RH, Hamid M, Serafin AM, Akudugu JM. Targeting the EGFR and PI3K pathways as a therapeutic strategy for prostate cancer. 58
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2014 (oral).
Hamunyela RH, Serafin AM, Hamid M, Maleka S, Akudugu JM. Novel approaches for targeting HER-2 and downstream signalling components for combined modality targeting of breast cancer. 58
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2014 (oral).
Hamid M, Maleka S, Hamunyela RH, Serafin AM, Akudugu JM. Novel treatment strategies for HER-2 positive breast cancer. 58
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2014 (oral).
Akudugu JM, Hamunyela RH, Hamid M, Maleka S, Serafin AM. Targeting the HER-2 signalling pathway as a combined modality therapeutic strategy for breast cancer. 3
rd
ScienceOne Conference on Drug Discovery and Development, Dubai, UAE, January 21-23, 2014 (Oral).
Vawda Z, Pitcher RD, Akudugu JM, Groenewald W, du Plessis AM. A comparison of the radiation dose for paediatric head CT scans from two multi-detector-row CT scanners at Tygerberg Hospital. 57
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2013 (oral).
Maleka S, Hamid M, Serafin AM, Hamunyela RH, Akudugu JM. Targeting the PSMA and PI3K pathways as a therapeutic strategy for prostate cancer. 57
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2013 (oral).
Hamid M, Serafin AM, Hamunyela RH, Maleka S, Akudugu JM. Novel treatment strategies for HER-2 positive breast cancer. 57
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2013 (oral).
Hamunyela RH, Hamid M, Maleka S, Serafin AM, Akudugu JM. Evaluation of radiation-induced activation of HER-2 and downstream signalling components for combined modality targeting of breast cancer. 57
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2013 (oral).
Akudugu JM, Howell RW. Design of novel cancer therapy cocktails. 56
th
Academic Year Day, Faculty of Medicine and Health Sciences, University of Stellenbosch, Tygerberg, South Africa, August 2012 (oral).