​Department of Paediatrics and Child Health



Professor Mariana Kruger​

Professor Mariana Kruger, MD, PhD, is a paediatric oncologist and ethicist.  She is currently a full professor of paediatrics and executive head of the department of Paediatrics and Child Health at Tygerberg Hospital, Stellenbosch University, as well as a founder member and co-principal director of South African Research Ethics Training Initiative (SARETI) UKZN, funded by Fogarty International, NIH, USA since it's inception in 2003 (currently in 3rd cycle). She is also an honorary professor in the School of Applied Human Sciences (Discipline of Psychology), University of KwaZulu-Natal. She is the past SIOP (International Society of Paediatric Oncology) Continental President for Africa (2012-2013). She has extensive managerial experience as head of department since 2001, as well as in senior management committees of both the School of Medicine of the Faculty of Health Sciences, University of Pretoria (2002 - 2009), as well as Stellenbosch University (2009 - present). Her teaching experience includes bioethics, research ethics, paediatrics and paediatric oncology at under- and postgraduate levels nationally and internationally. She currently serves at the chair of the Health Research Ethics Review Committee no 1, Faculty of Medicine and Health Sciences, Stellenbosch university and has served as chair on the University of Pretoria Health Research Ethics Review Committee and the Ethics Review Committee of the South African MRC, for several years. She has also served as chair of the HPCSA curriculum committee, member of the HPCSA Education and Registration Committee and has been a Board member of the HPCSA. Currently she serves as member of the following national and international committees: Member of the Central Clinical Committee of the South African Health Products Regulatory Authority (SAHPRA), the Senate Research Ethics Committee of Stellenbosch University, and member of the Postgraduate Committee of the Faculty of Medicine and Health Sciences Stellenbosch University. 

She has published 7 chapters, 52 peer reviewed publications and 41 peer reviewed conference abstracts. She published an African research ethics book, a peer reviewed book titled: “Research Ethics in Africa: A Resource for Research Ethics committees", with Drs Lyn Horn and Paul Ndebele, a project funded by an EDCTP grant in July 2014 (Doi 10.13140/2.1.2560.8646). She is a listed contributor to the SA MRC Ethical guidelines on HIV vaccine trials, and has been consulted by several research organizations (e.g., HAVEG (Trust funding see http://www.saavi.org.za/haveg.htm) and HEARD (NIH funding see http://www.heard.org.za/) at UKZN) on the ethics of conducting research with children. She is on the editorial board of the South African Journal of Child Health. She has been principal investigator on several paediatric clinical trials and co-investigator on others. She has been supervisor of senior postgraduate research projects in the field of research ethics, paediatrics (HIVAIDS & oncology), and physiotherapy. She has acted as referee for international journals and research agencies (of note Welcome Trust, South African NRF, Cancer, Journal of Medical Ethics, European Journal of Pediatrics, Pediatric Infectious Disease Journal, Journal of Clinical Oncology, South African Journal Child Health). Her clinical care includes the management of children with cancer and haematological disorders in Tygerberg Hospital.  She is a member of the International Society of Paediatric Oncology (SIOP) since 1992 by peer review process and is active in an advisory capacity regarding the management of childhood cancer and HIV/AIDS in children, as well as research ethics issues in paediatric research. She has participated in the organization of several international and national conferences regarding paediatrics, paediatric oncology and research ethics. She has been an invited speaker at national and international paediatrics, paediatric oncology and ethics conferences.