Clinical Pharmacology
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Division of Clinical Pharmacology

Publications 2014

1.  Von Birbra M, Rosenkranz B, Pretorius E, Rabie H, Edson C, Lenker U, Cotton M, Klinker H. Are lopinavir and efavirenz serum concentrations in HV-infected children in the therapeutic range in clinical practice? Paediatrics and International Child Health 2014; 34(2): 138-141.

2. Awortwe C, Bouic PJ, Masimirembwa CM, Rosenkranz B. Inhibition of Major Drug Metabolizing CYPs by Common Herbal Medicines used by HIV/AIDS patients in Africa – Implications for Herb-drug interactions. Drug Metabolism Letters 2014; 7: 83-95.​

3. Flepisi TB, Bouic P, Sissolak G, Rosenkranz B. Drug-drug interactions in HIV positive cancer patients. Biomedicine & Pharmacotherapy 2014; 68(5): 665-77.

4. Fasinu PS, Bouic P, Rosenkranz B. The inhibitory activity of the extracts of popular medicinal herbs on cyp1a2, 2c9, 2c19 and 3a4 and the implications for herb-drug interaction. Afr J Tradit Complement Altern Med 2014; 11(4): 54-61.

5. Manda VK, Dale OR, Awortwe C, Ali Z, Khan IA, Walker LA, Khan SI. Evaluation of drug interaction potential of Labisia pumila (Kacip Fatimah) and its constituents. Frontiers in Pharmacology 2014; 5 (178): 1-13.

6. de Kock L, Sy SKB, Rosenkranz B, Diacon AH, Prescott K, Hernandez KR, Yu M, Derendorf H, Donald PR. Pharmacokinetics of para-Aminosalicylic Acid in HIV-Uninfected and HIV-Coinfected Tuberculosis Patients Receiving Antiretroviral Therapy, Managed for Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis. Antimicrobial Agents and Chemotherapy 2014; 58(10): 6242-6250.

7. Awortwe C, Manda CK, Avonto C, Khan SI, Khan IA, Walker LA, Bouic PJ, Rosenkranz B. Echinacea purpurea up-regulates CYP1A2, CYP3A4 and MDR1 gene expression by activation of pregnane X receptor pathway. Xenobiotica 2014; 7: 1 – 12.

8. Flepisi BT, Bouic P, Sissolak G, Rosenkranz B. Biomarkers of HIV-associated cancer. Biomark Cancer 2014; 6: 11 – 20.

9. Awortwe C, Fasinu PS, Rosenkranz B. Application of Gaco-2 cell line in herb-drug interaction studies. Current approaches and challenges. J Pharm Pharm Sci 2014; 17(1): 1 – 19.

10. Sy SK, Innes S, Derendorf H, Cotton MF, Rosenkranz B. Estimation of intracellular concentration of stavudine triphosphate in HIV-infected children given a reduced dose of 0.5 milligrams per kilogram twice daily. Antimicrob Agents Chemother 2014; 58(2): 1084-91.

11.  Asiedu-Gyekye IJ, Mahmood SA, Awortwe C, Nyarko AK. A Preliminary safety evaluation of Polyhexamethylene Guanidine Hydrochloride. Int J Toxicol 2014; 33(6): 523-31.

12. Asiedu-Gyekye IJ, Frimpong Monso S, Awortwe C, Antwe DA, Nyarko AK. Micro- and Macro elemental composition and safety evaluation of nutraceutical maringa oleifera leaves. J Toxicol 2014.

13. Awortwe C, Asiedu-Gyekye IJ, Nkansah E, Adjei S. Unsweetend natural cocoa has anti-asthmatic potential. Int J Immunopathol Pharmacol 2014; 27(2): 203-12.

14.  Asiedu-Gyekye IJ, Antwi DA, Awortwe C, N'guessan BB, Nyarko AK. Short-term administration of an aqueous extract of kalanchoe integra var. crenata (Andr.) Cuf leaves produces no major organ damage in Sprague-dawley rats. J Ehhnopharmacol 2014; 151(2): 891-6.

15. Bekker A, Schaaf HS, Seifart HI, Draper HR, Werely CH, Cotton MF, Hesseling AC. Pharmacokinetics of Isoniazid in Low-Birth-Weight and Premature Infants. Antimicrobial Agents and Chemotherapy 2014; 58(4): 2229-2234.​