Haematological Pathology
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Division of Haematological Pathology

Diagnostic service

The Division of Haematology NHLS laboratory is SANAS accredited and provides a comprehensive 24-hour service to Tygerberg Hospital and some of the clinics and secondary hospitals in the Western Cape region. This service has been expanded with effect from April 2011 to include Eerste River Hospital and more peripheral clinics. The Division is one of the referral centres for samples from the Eastern Cape, particularly from Nelson Mandela Hospital.

An antenatal blood group typing service is provided to the hospital and large regions in the Western Cape in association with Groote Schuur Hospital.

 The Division of Haematology Tygerberg Consultant body is involved in all aspects of diagnostic service as well as research and training during the 2015 period.  Along with our current portfolio of specialised testing such as hereditary thrombophilia screening assasy, flow cytometry, and platelet function analysis, the following molecular based tests were implemented in 2015 by the division in conjunction with the Pathology Research Facility:

  1. Acute myeloid leukemia (AML): Screening for NPM1 (exon 12) mutations in patients with normal karyotype AML. 
  1. Chronic Myeloid leukemia: The validation of the GeneXpert for detection of p210 BCR –ABL transcript in patients with chronic myeloid leukemia has been completed and implemented
  1. Myeloproliferative neoplasms: MPL exons 10 have been implemented for 2015. CalR exon 9 mutation assay has been implemented.