Genetics
Welcome to Stellenbosch University

Theses & Dissertations

​DISSERTATIONS 2004 – 2017

 

2017

Mduna, SN
Unravelling the mystery of the shark genus Mustelus in Southern Africa using a population genomics approach.

 

2016

Bester, R
Small RNA profiling of grapevine leafroll-associated virus 3 infected grapevine plants.

Bitalo, DN
Population genetics of Galeorhinus galeus, Carcharhinus brachyurus and Rhinobatos annulatus- implications for regional fisheries and elasmobranch conservation.

Colling, J
Functional characterization of a putative signalling peptide TAXIMIN in the model plant Arabidopsis thaliana and a medicinal plant Sutherlandia frutescens L. R. Br.

 

2015 

Bierman, A
Mapping and survey sequencing of Dn resistance genes in Triticum aestivum L.

Loedolff, B
Functional roles of raffinose family oligosaccharides: Arabidopsis case studies in seed physiology, biotic stress and novel carbohydrate engineering

Sandenbergh, L
Identification of SNPs associated with robustness and greater reproductive success in the South African merino sheep using SNP chip technology

 

2014

Drögemoller, B
Investigation of genetic variation contributing to antipsychotic treatment response in a South African first episode schizophrenia cohort

Lamprecht, RL
Molecular characterisation of South African isolates of grapevine fanleaf virus and a new, associated satellite RNA

Swart, BL
The evolutionary history of the genus Seriola and the phylogeography and genetic diversity of S. lalandi (yellowtail) across its distribution range

 

2013

Rhode, C
Signatures of selection in natural and cultured abalone (Haliotis midae): A population genomics study
Strickland, N
In silico and functional analyses of the iron metabolism pathway.

 

2012

Wright, GEB
Molecular genetic analysis of two genes, CYP2D6 and COMT, in the schizophrenia-susceptibility locus on chromosome 22q in the Xhosa population 

 

2011

Roux, A
Reproduction of the South African abalone, Haliotis midae 

 

2010

du Preez, J
Developement and characterisation of Grapevine Virus based expression vectors

Heyns, I
Mapping and restructuring of an Aegilops kotschyi derived translocation segment in common wheat
Maree, H
Identification and characterisation of Grapevine leafroll-associated virus 3 genomic and subgenomic RNAs
Slabbert, R
Identification of growth related quantitative trait loci within abalone, Haliotis midae, using comparative microsatellite bulked segregant analysis
van der Merwe, M
Growth-related gene expression in Haliotis midae


2009

van der Merwe, AE
Population genetic structure and demographical history of South African abalone, Haliotis midae, in a conservation context

 

2004

Brink, D
Genetic improvement of growth rate in rainbow trout (Oncorhynchus mykiss)

 

MSc THESIS 2003 – 2017

2017

Aldrich, DJ
Characterisation of microRNA expression profiles of Vitis vinifera in response to grapevine leafroll-associated virus 3 infection

Badenhorst, R
Genetic diversity in a commercial black soldier fly, Hermetia illucens (Diptera: Stratiomydiae), population

Breeds, K
A targeted methylomic approach to investigating the virulence of Diuraphis noxia (Russian wheat aphid) biotypes to Triticum aestivum (L.) (wheat).

Jooste, T
The detection of Citrus tristeza virus genetic variants using pathogen specific electronic probes

Kuguru, G
Molecular species identification and spatio-temporal assessment of genetic diversity in the smooth hammerhead shark Sphyrna zygaena in South Africa

Kwalimba, L
Molecular fingerprinting and characterisation of the ARC's peach gene banks.

Lee, N
Engineering Brome mosaic virus as a potential drug delivery nanoparticle for prostate cancer

Meintjes, SW
Improvement of rust resistance and FHB resistance QTL in wheat through the application of an integrated biotechnology approach

Mostert, I
Genetic diversity and identification of putative recombination events in Grapevine rupestris stem pitting-associated virus

Mthembu, ZN
Development of a hairy root bioreactor from Stevia rebaudiana to produce steviol glycosides

Mushfieldt, K
Mutational analysis of E. coli maltodextrin metabolism

Nyawo, TA
Molecular fingerprinting and characterisation of the ARC's apricot and plum genebanks.

Oosthuizen, K
Characterising the viral and microbial diversity in old and young grapevines

Prince, E
Interactions between GWD and starch brabchinge enzyme in potato tuber starch metabolism.

Prins, R
The two oceans project : searching for novel carbohydrate sulfoconjugation enzymes

Swanepoel, CC
Characterisation of the glycoside hydrolase domain of a novel bi-functional metagenomic clone for use in the biofuel production industry

Van der Vyver, AE
Investigating the recovery phenotype phenomenon in Aster Yellows-infected Grapevine

 

2016

Hartzenberg, LC
Identification and manipulation of starch synthases from marama bean and potato

Janse van Rensburg, HC
The Arabidopsis GolS1 promotor as a potential biosensor for heat stress and fungal infection?

Kitchin, N
Genomic resource development for the South African scallop, Pecten sulcicostatus

Le Roux, ML
Using Innovative Approaches to Enhance Abiotic Stress Tolerance in Wheat.

Loubser, J
Tools for strigolactone research : Towards a strigolactone-responsive promoter and a strigolactone-activity inhibitor

Masoabi, M
Biotechnological approaches for sugarcane enhancement - Drought tolerance and cell wall manipulation.

Moller EL
A diallel study of Secale cereale

Niemandt, M
Genetic marker resources for application in Cyclopia species

Rossouw, MJ
Application of plant growth promoting substances and arbuscular mycorrhizal fungi for phytostabilisation of mine tailings

Steyn, LJ
Karyotyping and in silico characterisation of the chromosomes of Diuraphis noxia (Hemiptera: Aphididae)

Strydom, L
Mutational analysis of genes involved in glycogen degradation in Escherichia coli

Van Zyl, I
The re-evaluation of pollen mediated gene flow within small grain

Versfeld, WF
Nile crocodile (Crocodylus niloticus) genetic diversity and population structure, within the lower Kunene and Okavango Rivers of northern Namibia

Visser, I
RNAi of selected insect genes

2015

Botha, SC
Assessing the cyto-genotoxic impacts of un-neutralised and pH-neutralised acid mine drainage on the human breast cancer cell line, MCF-7

Dale-Kuys, RC
Linkage disequilibrium in the South African abalone, Haliotis midae

Dempers, D
Overexpression of α-acetolactate decarboxylase and acetoin reductase/2,3-butanediol dehydrogenase in Arabidopsis thaliana

Denkhaus, E
Using XhLEA, a group 1 vegetative Late Embryogenesis Abundant protein to aid water deficit tolerance in plants and microbes

De Villiers, IJ
Mutagenesis studies of a glycoside hydrolase family 2 enzyme

De Villiers, RM
Reverse genetic analysis of gene Pp1s148_40v6 in Physcomitrella patens : an AtMAX2 orthologue?

Fernhout, J
Isolation and characterisation of genes involved in carbon and chlorophyll metabolism in Saccharum species hybrids

Frazenburg, L
The development of a diagnostic assay for nepoviruses in grapevine

Higgins, F
Molecular genetic analyses of antipsychotic pharmacogenes in a South African first episode schizophrenia cohort

Jayakumar, R
Functional identification of the chloroplastic raffinose transporter from arabidopsis

Jewell, JF
​The analysis of glycogen phosphate and glucose-1,6-bisphosphate metabolism in escherichia coli

Lekgari, GLP
Over-expressing ArabidopsisArabidopsis Myb transcription factors in Salvia stenophylla and sugarcane and development of micropropagation protocol for Salvia repens

Marais, C
Screening, isolating and characterizing acetyl xylan esterase enzymes from a novel ecological niche

Mhelembe, KG
Molecular characterisation of ARC pome fruit collections in South Africa

Molenaar, N
Determination of the virus diversity associated with Grapevine leafroll disease

Ovenden, ES
Investigating the functional significance of GWAS associations relating to antipsychotic treatment response

Rossouw, C
Development and application of molecular markers via NGS in ground shark species

Smyth, N
The determination of the spatial and temporal distribution of Aster Yellows phytoplasma in grapevine

Stander, EA
Roles of disproportionating enzymes in the moss Physcomitrella patens

Suidtgeest, F
Evaluation of two pathogen-derived resistance strategies for Grapevine leafroll-associated virus 3

Vlok, AC
Genetic assessment of five breeding populations of abalone (Haliotis midae) through a comparative Performance Testing Scheme

 

2014

Carstens, R
The incidence and distribution of grapevine yellows disease in South African vineyards

Cofee, M
Analysis of schizophrenia susceptibility variants identified by GWAS : a bioinformatics and molecular genetics approach

Cowie, D
Iron and Tuberculosis pathogenesis

De Jager, L
Characterization of the mitochondrial genomes of Diuraphis noxia biotypes

Fisher, NM
Gene silencing in bread wheat (Triticum aestivum L.) following a biolistics approach

Maduna, SN
Genetic diversity and population genetic structure in the South African commercially important shark species, the common smoothhound (Mustelus mustelus)

Mbwanji KC
Inducing mutations in bread wheat (Triticum aestivum L.) using chemical treatments

Nieuwoudt, E
Effect of genetic variants in genes encoding two nuclear receptors (PXR and CAR) on efavirenz levels and treatment outcome in South African HIV-infected females

Sittmann, M
Mutation analysis of the promoter region of CYBRD1, HFE, LTF, HAMP and SLC40A1 in a Tuberculosis cohort

Springfield, LS
Pyramiding of rust resistance genes in wheat utilizing male sterility mediated marker-assisted recurrent selection

Veikondis, R
Genetic characterisation of fungal disease resistance genes in grapevine using molecular marker technology

 

2013

Difford, G
Critical assessment of the "internal reference" method to eliminate non-genetic effects within a Combined Family Selection program on the abalone species Haliotis midae

Espach, Y
The detection of mycoviral sequences in grapevine using next-generation sequencing

Gerber, M
Quantitative assessment of yield traits between family groups of the cultured abalone, Haliotis midae, during the process of canning

Sewpersad, N
Mining the South African Sugar Cane Research Insitute's research database to categorize the reaction of released sugarcane varieties to water stress 

Smit, C
Pyramiding of novel rust resistance genes in wheat, utilising marker assisted selection and doubled haploid technology

Spinas, N
The efficacy of the antimicrobial peptides D4E1, VvAMP-1 and Snakin1 against the grapevine pathogen aster yellows phytoplasma

 

2012

Bester, R

Sequencing and detection of a new strain of Grapevine leafroll-associated virus 3 in South Africa 

Bitalo, D
Development of markers for triticale cultivar identification

Blaauw, S
SNP screening and validation in Haliotis midae 
 
De Groot, S
Initiation of a pre-breeding program for enhancing genetic resistance against wheat rust.

Du Plessis, J
Medium-throughput SNP genotyping and linkage mapping in Haliotis midae

Jansen, S
Linkage mapping in Haliotis midae using gene-linked markers

Rohrich, C
The influence of pharmacogenetic traits and efavirenz levels on treatment outcome in HIV-positive South African women

 

2011 

Coetzee, K
Evaluation of the crossability between small grains

Ntladi, S 
The development and implementation of phenotypic and molecular marker based differentiation systems for triticale

Prins, N 
Assesment of components of variance and covariance of production traits in the indigenous abalone, Haliotis midae

van Schalkwyk, H
Determination of heritibility of production traits of the indigenous abalone Haliotis midae, with specific reference to yield and quality related traits during live export

Visser, M
An evaluation of the efficacy of antimicrobial peptides against grapevine pathogens

 

2010

Coetzee, B
Virome in the vineyard

Dix, R 
Investigation into the suitability of ethanol production from wheat
 
Drögemöller, B 
Sequence diversity and characterization of genetic variants in the CYP2C19 gene in South African individuals

Hepple, J
Linkage mapping in Haliotis midae

le Maitre, N 
Population genetic study if wheat rusts affecting cereal production in the Western Cape

Noach, LC 
The molecular characterisation of South African isolates of Grapevine Rucpestris Stem-Pitting associated Virus (GRSPaV) 

Rhode, C 
Developement of gene-linked molecular markers in Souh African abalone (Haliotis midae) using an in silico mining approach

Sandenbergh, L
Optimization of gene transfer in Haliotis midae by means of polyplex mediation

Vervalle, J
Characterisation of the SLC40A1 gene implicated in iron metabolism

Wessels, E
Development of a wheat nursery with pyramided, species-derived rust resistance genes

 

2009

Bekker, TA 
Molekulêre karakterisering van 'n Triticum speltoides-verhaalde translokasie en verkorte vorms

Blignaut, M 
The molecular and biological characterisation of ORF5 of three South African variants of Grapevine Vitivirus A

Bosman, M 
Molecular genetic analysis of abruptio placentae

De Jager, J 
Molecular characterisation of Annexin II in pre-eclampsia

Kotze, L 
Verkorting van die Ae. peregrina-verhaalde Lr59-translokasie van koring

Malan, S 
QPCR as a versatile tool for virus detection and transgenic plant analysis

McGregor, NW 
Characterisation of the genes HFE, HAMP and HJV implicated in iron metabolism

Postma, A 
Molecular characterisation of the LGALS13 gene

Strickland, NJ 
Molecular-genetic analysis of ceruloplasmin in oesophageal cancer

Tsupko, Y
Investigation into the suitability of spring triticale for bio-ethanol prodution in the Western Cape

 

2008

Badenhorst, D
Development of AFLP markers for Haliotis midae for linkage mapping

Badenhorst, PE
Attempt to shorten the Lr56/Yr38 translocation (wheat) derived from Aegilops sharonensis

Hallendorff, M
Ironing out haemochromatosis: a study of an Indian family

Holm, K
Gene discovery: Construction of a DNA library for the whole organism transcriptome of the vine mealybug, Planococcus ficus Signoret

Kerr, M
Towards the identification and isolation of VvPNP

Liebenberg, A
The development of an Enzyme linked immunosorbent Assay (ELISA) for the detection of Grapvine Fanleaf Nepo virus (GFLV)

Panton, N
Mutation analysis of four genes implicated in iron hemeostasis in porphyria cutanea tarda (PCT) patients

Schoonbee, L
The effect of triploidy on the growth and survival of the indigenous abalone, Haliotis midae, over a 24 months period under commercial rearing conditions

van den Berg, NC
Microsatellite marker development and parentage assignment in Haliotis midae

Visser, HJ
Molekulêre merking van Thinopyrum distichum chromosome betrokke by soutverdraagsaamheid en die karakterisering van digeneriese (Triticum/Thinopyrum) en trigeneriese (Triticum/Secale/Thinopyrum) sekondêre hibriede
 
 

2007

Bloem, L
Multiple sclerosis and iron

Booley, F
Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload in the South African population

Bruiners N
Molecular genetic analysis of preterm labour

Du Plessis, N
Analysis of genes variants in the ALAS1 and HMOX1 genes in variegate porphyria (VP) patients

Hitzeroth, A
Association of genetic variants and the susceptibility to tardive dyskinesia (TD) in schizophrenic patients

Honing, J
Evaluation and implementation of DNA-based diagnostic methodology to distinguish wheat genotypes

Human, VR
Molecular analysis of genes involved in iron overload implicated in oesophageal cancer

Parathyras, J
Molecular genetic analysis of varied clinical responses to antiretroviral drug compounds in South African populations – a pharmacogenetics study

Ruivo, NR
Microsatellite genotyping of contributing broodstock and selected offspring of Haliotis midae submitted to a growth performance recording scheme

Stolk, M
Characterisation of novel TAC3 and TACR3 gene variants and polymorphisms in patients with pre-eclampsia

Truter, E
Genetic association analysis of polymorphisms in three cytochrome P450 genes and treatment-outcome in Xhosa schizophrenic patients

 

2006

Desodt, KGP
Mutation of screening of pre-eclampsia candidate genes, LEP (ob) and LEPR

Engelbrecht, M
Screening the genome of GLRaV-2 for proteins with RNA silencing suppressor activity and the construction of a tandem silencing vector to induce simultaneous silencing of two genes

 

2005

Du Preez, J
The construction of an infectious clone of Grapevine virus A

Heyns, IC
Mapping of chromosome arm 7DL of Triticum aestivum L

Ockert, CM
Identification of molecular markers for diagnostic identification of the intracellular prokaryote associated with the appearance of Withering Syndrome in the abalone, Haliotis midae

 

2004

De Beer, M
Induction of triploidy in the South African abalone, Haliotis midae, by method of hydrostatic pressure

Loubser, D
Molecular tagging of Thinopyrum distichum chromosomes involved in salt tolerance

Rhode, A
Genetiese verenigbaarheid tussen taksonomiese verwante spesies van die genus Leucadendron

Rose, BA
Molecular characterization of the grapevine chloroplast genome

Slabbert, R
Molecular analysis of genetic variation and relationships within the population of abalone (Haliotis midae) at the Sea Plant Products abalone hatchery

Van Eeden, C
Isolation, cloning and transformation of RSP-CP genes for PTG5

Whitehead, CB
Childhood hereditary deafness and its cause within South Africa

 

2003

Christians, GE
Identification of molecular markers linked to woolly apple aphid (Eriosoma lanigerum Hausmann) resistance in apple

Gerber, J
Cytochrome P450 polymorphisms; relevance in two South African disease populations

Koegelenberg, AJ
Molecular epidemiological study of variegate porphyria (VP) to determine the frequency of the founder gene mutation

Maree, HJ
The expression of Dianthin: A ribosome inactivating protein

Robson, J
The construction of an expression vector for the transformation of the grape chloroplast genome

Vorster, G
A quantitative genetic analysis of the effect of cross breeding on the growth rate of the South African abalone (Haliotis midae)

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