This Chair, held by Professor Anneke Hesseling, Director of the Desmond Tutu TB Centre and Distinguished Professor in Paediatrics and Child Health, focuses on novel and transformative strategies to improve tuberculosis prevention, diagnosis, and treatment in children, using family-centered approaches in the context of broader lung and child and maternal health. Evaluation of novel drug regimens across the age, disease and drug resistance spectrum is a key priority with pharmokinetic trials of novel and repurposed drugs in children, adolescents, and pregnant women a pivotal research focus. Diagnostic and biomarkers is another strong focus, given the challenges of diagnosis tuberculosis in children. Her group’s translational clinical research is underpinned by robust surveillance, epidemiological research, health systems strengthening, mathematical modelling and socio-behavioural research.​