Welcome to Stellenbosch University

Division of Molecular B​iology and Human Genetics


​​About us​​​​​

The TB Drugs research group focus is on the development of antimycobacterial biopharmaceuticals, which could be either small molecules or polypeptides (e.g bacteriocins) for application in drug development for both pulmonary and extrapulmonary TB. The latter largely concentrates on the central nervous system, hepatic, cardiovascular and renal systems. 

​Our approach in drug developm​ent is interdisciplinary and incorporates the use of bioactive constituents derived from microbial symbionts associated with immobile aquatic invertebrates such as marine sponges and ascidians. Our most bioactive agents are further fabricated into organoboron compounds (halogenated cyclic boronates) using a variety of semi-synthetic approaches. ​