TB Drugs
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Division of Molecular Biology & Human Genetics

​​​​​​​​​TB Drugs: Targets & Developments

Developing and testing inhibitors that are active against the enzymes of mycothiol/ergothioneine and Nitrogen metabolism pathways in Mycobacterium tuberculosis as possible new antitubercular drugs. We are also investigating the gene expression and proteomic changes in macrophages infected with pathogenic and non-pathogenic mycobacterial strains, in search of host factors that influence survival of mycobacteria in macrophages. The ultimate aim is to develop host-directed anti-TB therapeutics.