​​Stellenbosch University Immunology Research Group

Publications

20​12

1. Acute helminth infection enhances early macrophage mediated control of mycobacterial infection.

Du Plessis N, Kleynhans L, Thiart L, van Helden PD, Brombacher F, Horsnell WG, Walzl G. Mucosal Immunol. 2012 Dec 19

http://www.ncbi.nlm.nih.gov/pubmed/23250274

2. Diversity of Mycobacterium tuberculosis Isolates from New Pulmonary Tuberculosis Cases in Addis Ababa, Ethiopia.

Mihret A, Bekele Y, Loxton AG, Jordan AM, Yamuah L, Aseffa A, Howe R, Walzl G.Tuberc Res Treat. 2012;2012:892079. Epub 2012 Nov 22.

http://www.hindawi.com/journals/trt/2012/892079/

3. Detecting Tuberculosis Infection in HIV-Infected Children: A Study of Diagnostic Accuracy, Confounding and Interaction.

Mandalakas AM, van Wyk S, Kirchner HL, Walzl G, Cotton M, Rabie H, Kriel B, Gie RP, Schaaf HS, Hesseling AC. Pediatr Infect Dis J. 2012 Nov 28.

http://www.ncbi.nlm.nih.gov/pubmed/23190784

4. Plasma cytokines and chemokines differentiate between active disease and non-active tuberculosis infection.

Mihret A, Bekele Y, Bobosha K, Kidd M, Aseffa A, Howe R, Walzl G. J Infect. 2012 Nov 20. doi:pii: S0163-4453(12)00339-8.

http://www.ncbi.nlm.nih.gov/pubmed/23178506

5. Serodiagnostic markers for the prediction of the outcome of intensive phase tuberculosis therapy.

Baumann R, Kaempfer S, Chegou NN, Nene NF, Veenstra H, Spallek R, Bolliger CT, Lukey PT, van Helden PD, Singh M, Walzl G. Tuberculosis (Edinb). 2012 Nov 2

http://www.ncbi.nlm.nih.gov/pubmed/23127778

6. BDNF Val66Met and DRD2 Taq1A polymorphisms interact to influence PTSD symptom severity: a preliminary investigation in a South African population.

Hemmings SM, Martin LI, Klopper M, van der Merwe L, Aitken L, de Wit E, Black GF, Hoal EG, Walzl G, Seedat S. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Jan 10;40:273-80

http://www.ncbi.nlm.nih.gov/pubmed/23103549

7. Plasma Level of IL-4 Differs in Patients Infected with Different Modern Lineages of M. tuberculosis.

Mihret A, Bekele Y, Loxton AG, Aseffa A, Howe R, Walzl G. J Trop Med. 2012;2012:518564

http://www.hindawi.com/journals/jtm/2012/518564/

8. Effect of Ascaris Lumbricoides specific IgE on tuberculin skin test responses in children in a high-burden setting: a cross-sectional community-based study.

Van Soelen N, Mandalakas AM, Kirchner HL, Walzl G, Grewal HM, Jacobsen M, Hesseling AC. BMC Infect Dis. 2012 Sep 11;12:211

http://www.biomedcentral.com/1471-2334/12/211

9. Biomarkers of inflammation, immunosuppression and stress with active disease are revealed by metabolomic profiling of tuberculosis patients.

Weiner J 3rd, Parida SK, Maertzdorf J, Black GF, Repsilber D, Telaar A, Mohney RP, Arndt-Sullivan C, Ganoza CA, Faé KC, Walzl G, Kaufmann SH. PLoS One. 2012;7(7):e40221

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0040221

10. Detection and treatment of subclinical tuberculosis.

Robertson BD, Altmann D, Barry C, Bishai B, Cole S, Dick T, Duncan K, Dye C, Ehrt S, Esmail H, Flynn J, Hafner R, Handley G, Hanekom W, van Helden P, Kaplan G, Kaufmann SH, Kim P, Lienhardt C, Mizrahi V, Rubin E, Schnappinger D, Sherman D, Thole J, Vandal O, Walzl G, Warner D, Wilkinson R, Young D. Tuberculosis (Edinb). 2012 Nov;92(6):447-52

http://www.ncbi.nlm.nih.gov/pubmed/22819716

11. Potential of host markers produced by infection phase-dependent antigen-stimulated cells for the diagnosis of tuberculosis in a highly endemic area.

Chegou NN, Essone PN, Loxton AG, Stanley K, Black GF, van der Spuy GD, van Helden PD, Franken KL, Parida SK, Klein MR, Kaufmann SH, Ottenhoff TH, Walzl G. PLoS One. 2012;7(6):e38501

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0038501

12. Well-quantified tuberculosis exposure is a reliable surrogate measure of tuberculosis infection.

Mandalakas AM, Kirchner HL, Lombard C, Walzl G, Grewal HM, Gie RP, Hesseling AC. Int J Tuberc Lung Dis. 2012 Aug;16(8):1033-9

http://www.ncbi.nlm.nih.gov/pubmed/22692027

13. Development of a diagnostic gene expression assay for tuberculosis and its use under field conditions in African buffaloes (Syncerus caffer).

Parsons SD, Menezes AM, Cooper D, Walzl G, Warren RM, van Helden PD. Vet Immunol Immunopathol. 2012 Aug 15;148(3-4):337-42

http://www.ncbi.nlm.nih.gov/pubmed/22683147

14. Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis.

Riou C, Perez Peixoto B, Roberts L, Ronacher K, Walzl G, Manca C, Rustomjee R, Mthiyane T, Fallows D, Gray CM, Kaplan G. PLoS One. 2012;7(5):e36886

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036886

15. Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa.

Mlisana K, Naicker N, Werner L, Roberts L, van Loggerenberg F, Baxter C, Passmore JA, Grobler AC, Sturm AW, Williamson C, Ronacher K, Walzl G, Abdool Karim SS.

J Infect Dis. 2012 Jul 1;206(1):6-14

http://www.ncbi.nlm.nih.gov/pubmed/22517910

16. Heparin-binding hemagglutinin induces IFN-γ(+) IL-2(+) IL-17(+) multifunctional CD4(+) T cells during latent but not active tuberculosis disease.

Loxton AG, Black GF, Stanley K, Walzl G. Clin Vaccine Immunol. 2012 May;19(5):746-51

http://www.ncbi.nlm.nih.gov/pubmed/22461525

17. Potential of novel Mycobacterium tuberculosis infection phase-dependent antigens in the diagnosis of TB disease in a high burden setting.

Chegou NN, Black GF, Loxton AG, Stanley K, Essone PN, Klein MR, Parida SK, Kaufmann SH, Doherty TM, Friggen AH, Franken KL, Ottenhoff TH, Walzl G. BMC Infect Dis. 2012 Jan 20;12:10

http://www.biomedcentral.com/1471-2334/12/10

18. Baseline predictors of sputum culture conversion in pulmonary tuberculosis: importance of cavities, smoking, time to detection and W-Beijing genotype.

Visser ME, Stead MC, Walzl G, Warren R, Schomaker M, Grewal HM, Swart EC, Maartens G. PLoS One. 2012;7(1)

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0029588

19. Genital tract inflammation during early HIV-1 infection predicts higher plasma viral load set point in women.

Roberts L, Passmore JA, Mlisana K, Williamson C, Little F, Bebell LM, Walzl G, Abrahams MR, Woodman Z, Abdool Karim Q, Abdool Karim SS. J Infect Dis. 2012 Jan 15;205(2):194-203

http://www.ncbi.nlm.nih.gov/pubmed/22190580​