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Researchers return to communities to deliver results of landmark HIV prevention study
Author: Kim Cloete
Published: 07/05/2019

Over the past few weeks, people from nine communities in and around Cape Town and the Winelands district have gathered to hear about the primary outcome results of the HPTN 071 (PopART) study. It is the largest study into HIV prevention to date and was carried out in South Africa and Zambia. 

Community members and local leaders, fieldworkers and clinic staff from the nine South African study sites met at town halls and venues in the communities to attend the dissemination meetings. 

“We would not have been able to undertake this pivotal HIV prevention trial without the support of people in the communities in which we worked. We wanted to thank them for it and reflect on how their participation has made a difference," said Dr Peter Bock, Research Clinician at the Desmond Tutu TB Centre (DTTC) at Stellenbosch University and HPTN 071 (PopART) Co-Principal Investigator for South Africa. 

Over a period of four years, Community HIV Care Providers (CHiPS) went door to door in 21 communities in South Africa and Zambia, offering a package of HIV prevention services. They provided HIV testing and counselling, condoms, and screening and education on sexually transmitted infections and tuberculosis. They linked HIV positive clients to care and Antiretroviral Treatment (ART) at clinics. 

The trial found that in-home testing, combined with referring people living with HIV to care and treatment at clinics could substantially reduce new HIV infections. 

Community members and local leaders welcomed the results and said they had been proud to play their part in raising awareness about HIV prevention and helping to bring down the high HIV infection rate through increased HIV testing and treatment. 

“Whatever can be done to prevent illness will not only save many lives, but will also be cost-effective in the long run," said Aidan Stowman, Speaker for the Drakenstein municipality in Paarl, Western Cape, at one of the community dissemination events. 

He also welcomed the way the results had been shared with the community. 

“We thank you for keeping your promise to report on the results." 

Members of Community Advisory Boards (CAB) set up for the study played a key role.  The members volunteered their services for free and were a critical link between the researchers, community members and the clinics. They offered advice, encouraged people to test and get treated for HIV and helped to smooth out any challenges within the community. 

Community members also relayed their experiences during the trial, saying the message about preventing HIV through testing and going on treatment had been spread far and wide by the CHiPS, who tested people once a year for four years. Several study participants said going onto antiretroviral treatment had been a lifeline. 

At each of the events, there was either a performance by a talented marimba band or an uplifting, meaningful and sometimes humorous performance from a local arts, drama or performance group, carrying a message about HIV prevention. People in each site shared their experiences during the study while questions from community members were welcomed. 

“It is so important to tell people in communities about the results of the study. They have invested their time and interest in the study over the past few years and deserve to know the outcome," said Nomtha Mandla, Population Cohort Project Manager for HPTN 071 (PopART) in South Africa. 

A separate event was held to present the primary outcome results to other partners and stakeholders who have been pivotal to the running and success of the study. Representatives from the US Embassy in South Africa, the City of Cape Town Health Department, the Western Cape Department of Health, NGO implementing partners - Kheth'Impilo and Anova - and Stellenbosch University leadership, attended the meeting. 

“Partnerships were at the heart of the HPTN 071 (PopART) study. We are very grateful to everyone who worked together over the years towards the greater goal of helping to bring down the rate of HIV in our communities and further afield," said Professor Nulda Beyers, Principal Investigator of the HPTN 071 (PopART) study in South Africa. 

The DTTC hopes the lessons learnt from the trial will help to improve the delivery of health services. The DTTC worked closely with the Western Cape Department of Health and the City of Cape Town Health Department and believes that through close collaboration of academics and health service providers, the delivery of health to communities can be improved. 

The HPTN 071 (PopART) study was sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) with primary funding from the US President's Emergency Plan for AIDS Relief (PEPFAR), which is administered by the Office of the US Global AIDS Coordinator and Health Diplomacy in the US Department of State. Additional funding was provided by the International Initiative for Impact Evaluation (3ie) with support from the Bill & Melinda Gates Foundation, as well as by NIAID, the National Institute on Drug Abuse (NIDA) and the National Institute of Mental Health (NIMH), all part of NIH.


Banner photo: A community drama group staging a performance focused on HIV and TB.

Photo insert 1: Dissemination of the primary findings of the HPTN 071 (PopART) study at a community event in Paarl.

Photo insert 2: Prof Nulda Beyers (right) and one of the members of the HPTN 071 (PopART) team at the event.