​Journal Articles (subsidised)

ABIDIN MZ, SARAVANAN T, STRAUSS E, POELARENDS GJ. The broad amine scope of pantothenate synthetase enables the synthesis of pharmaceutically relevant amides. Organic and Biomolecular Chemistry 2021; 19:4515-4519.

ALBERTS JF, DAVIDS I, MOLL W-D, SCHATZMAYR G, BURGER H-M, SHEPHARD GS, GELDERBLOM WCA. Enzymatic detoxification of the fumonisin mycotoxins during dry milling of maize. Food Control 2021; 123:107726, 9 pages.

APPANNA N, GIBSON H, GANGITANO E, DEMPSTER NJ, MORRIS K, GEORGE S, ARVANITI A, GATHERCOLE LL, KEEVIL B, PENNING TM, STORBECK K, TOMLINSON JW, NIKOLAOU N. Differential activity and expression of human 5β-reductase (AKR1D1) splice variants. JOURNAL OF MOLECULAR ENDOCRINOLOGY 2021; 66(3):181-194.

BARNARD L, DU TOIT T, SWART AC. Back where it belongs: 11β-hydroxyandrostenedione compels the re-assessment of C11-oxy androgens in steroidogenesis. Molecular and Cellular Endocrinology 2021; 525:111189, 17 pages.

BARNARD L, SCHIFFER L, LOUW-DU TOIT R, TAMBLYN JA, CHEN S, AFRICANDER DJ, ARLT W, FOSTER PA, STORBECK K. 11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool. Endocrinology 2021; 162(3):1-11.

BICK AJ, LOUW-DU TOIT R, SKOSANA SB, AFRICANDER DJ, HAPGOOD JP. Pharmacokinetics, metabolism and serum concentrations of progestins used in contraception. PHARMACOLOGY & THERAPEUTICS 2021; 222:107789, 18 pages.

BINATI RL, DU TOIT M, SNOEP JL, SALVETTI E, TORRIANI S. Transcriptional and Metabolic Response of Wine-Related Lactiplantibacillus plantarum to Different Conditions of Aeration and Nitrogen Availability. Fermentation 2021; 7:68, 16 pages.

BOOYSEN E, RAUTENBACH M, STANDER MA, DICKS LMT. Profiling the Production of Antimicrobial Secondary Metabolites by Xenorhabdus khoisanae J194 Under Different Culturing Conditions. Frontiers in Chemistry 2021; 9:article 626653, 15 pages.

CHAKAFANA G, MUDAU PT, ZININGA T, SHONHAI A. Characterisation of a unique linker segment of the Plasmodium falciparum cytosol localised Hsp110 chaperone. International Journal of Biological Macromolecules 2021; 180:272-285.

CHAKAFANA G, MUDAU PT, ZININGA T, SHONHAI A. Supporting data on characterisation of linker switch mutants of Plasmodium falciparum heat shock protein 110 and canonical Hsp70. Data in Brief 2021; 37:107177, 11 pages.

CHAKAFANA G, SPRACKLEN TF, KAMULI S, ZININGA T, SHONHAI A, NTUSI NAB, SLIWA K. Heat Shock Proteins: Potential Modulators and Candidate Biomarkers of Peripartum Cardiomyopathy. Frontiers in Cardiovascular Medicine 2021; 8:633013, 18 pages.

CLEMENTS TL, RAUTENBACH M, NDLOVU T, KHAN S, KHAN W. A Metabolomics and Molecular Networking Approach to Elucidate the Structures of Secondary Metabolites Produced by Serratia marcescens Strains. Frontiers in Chemistry 2021; 9:Article 633870, 16 pages.

DU TOIT T, SWART AC. Turning the spotlight on the C11-oxy androgens in human fetal development. Journal of Steroid Biochemistry and Molecular Biology 2021; 212:105946, 14 pages.

GRZEGORZEWSKI J, BRANDHORST J, GREEN KA, ELEFTHERLADOU D, DUPORT Y, BARTHORSCHT F, KÖLLER A, YU JIA KE D, DE ANGELIS S, KÖNIG M. PK-DB: pharmacokinetics database for individualized and stratified computational modeling. Nucleic Acids Research 2021; 49:D1358-D1364.

HARDY RS, BOTFIELD H, MARKEY K, MITCHELL JL, ALIMAJSTOROVIC Z, WESTGATE CSJ, SAGMEISTER M, FAIRCLOUGH RJ, OTTRIDGE RS, YIANGOU A, STORBECK K, ET AL. 11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension. Journal of Clinical Endocrinology and Metabolism 2021; 106(1):174-187.

HOFMEYR JS. A biochemically-realisable relational model of the self-manufacturing cell. Biosystems 2021; 207:104463, 15 pages.

HORN S, SNOEP JL, VAN NIEKERK DD. Uncovering the efects of heterogeneity and parameter sensitivity on within‑host dynamics of disease: malaria as a case study. BMC Bioinformatics 2021; 22:384, 21 pages.

KAYAMBA F, MALIMABE T, ADEMOLA IK, POOE OJ, KUSHWAHA ND, MAHLALELA M, VAN ZYL RL, GORDON M, MUDAU PT, ZININGA T, SHONHAI A, NYAMORI VO, KARPOORMATH R. Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2021; 217:113330, 20 pages.

LILLY M, RHEEDER JP, PROCTOR RH, GELDERBLOM WCA. FUM gene expression and variation in fumonisin production of clonal isolates of Fusarium verticillioides MRC 826. World Mycotoxin Journal 2021; 14(2):121-137.

LOUW C, VAN SCHALKWYK FJ, CONRADIE R, LOUW RP, ENGELBRECHT Y, STORBECK K, SWART AC, VAN NIEKERK DD, SNOEP JL, SWART P. Computational modelling of the Δ4 and Δ5 adrenal steroidogenic pathways provides insight into hypocortisolism. Molecular and Cellular Endocrinology 2021; 526:111194, 8 pages.

MAGANGANA TP, MAKUNGA NP, LA GRANGE C, STANDER MA, FAWOLE OA, OPARA UL. Blanching Pre-Treatment Promotes High Yields, Bioactive Compounds, Antioxidants, Enzyme Inactivation and Antibacterial Activity of 'Wonderful' Pomegranate Peel Extracts at Three Different Harvest Maturities. Antioxidants 2021; 10(1119):1-25.

MAGANGANA TP, STANDER MA, MASONDO N, MAKUNGA NP. Steviol glycoside content and essential oil profiles of Stevia rebaudiana Bertoni in response to NaCl and polyethylene glycol as inducers of salinity and drought stress in vitro. Plant Cell, Tissue and Organ Culture 2021; 145:1-18.

MAKUMIRE S, DONGOLA TH, CHAKAFANA G, TSHIKONWANE L, CHAUKE CT, MAHARAJ T, ZININGA T, SHONHAI A. Mutation of GGMP Repeat Segments of Plasmodium falciparum Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding. International Journal of Molecular Sciences 2021; 22:2226, 22 pages.

MASIKE K, STANDER MA, DE VILLIERS AJ. Recent applications of ion mobility spectrometry in natural product research. Journal of Pharmaceutical and Biomedical Analysis 2021; 195:113846: 8.

MASOUDI Y, VAN RENSBURG W, JENKINS B, RAUTENBACH M. The Influence of Cellulose-Type Formulants on Anti-Candida Activity of the Tyrocidines. Antibiotics 2021; 10(5):597, 16 pages.

MOJICA-BENAVIDES M, VAN NIEKERK DD, MIJALKOV M, SNOEP JL, MEHLIG B, VOLPE G, GOKSÖR M, ADIELS CB. Intercellular communication induces glycolytic synchronization waves between individually oscillating cells . Proceedings of the National Academy of Sciences of the United States of America 2021; 118(6):e2010075118, 8 pages.

MOSTERT KJ, SHARMA N, VAN DER ZWAAG M, STAATS R, KOEKEMOER L, ANAND R, SIBON OCM, STRAUSS E. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chemical Biology 2021; 16:2401-2414.

RAS TA, STRAUSS E, BOTES A. Evaluating the Genetic Capacity of Mycoplasmas for Coenzyme A Biosynthesis in a Search for New Anti-mycoplasma Targets. Frontiers in Microbiology 2021; 12:Article 791756, 18 pages.

RAUTENBACH M, KUMAR V, VOSLOO JA, MASOUDI Y, VAN WYK RJ, STANDER MA. Oligomerisation of tryptocidine C, a Trp-rich cyclodecapeptide from the antimicrobial tyrothricin complex. Biochimie 2021; 181:123-133.

ROHWER JM, SCHUTTE C, VAN DER SLUIS R. Functional Characterisation of Three Glycine N-Acyltransferase Variants and the Effect on Glycine Conjugation to Benzoyl–CoA. International Journal of Molecular Sciences 2021; 22:3129, 17 pages.

SAMODIEN S, DE KOCK M, JOUBERT E, SWANEVELDER S, GELDERBLOM WCA. Differential Cytotoxicity of Rooibos and Green Tea Extracts against Primary Rat Hepatocytes and Human Liver and Colon Cancer Cells ? Causal Role of Major Flavonoids. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL 2021; 73(10):2050-2064.

SCHIFFER L, BOSSEY A, KEMPEGOWDA P, TAYLOR AE, AKERMAN I, SCHEEL-TOELLNER D, STORBECK K, ARLT W. Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens. European Journal of Endocrinology 2021; 184(3):357-367.

SIANGWATA S, WILLIAMS C, OMOSUN N, NGUBANE S, SMITH GS. Core- and peripheral-functionalised metallodendrimers for hydroformylation reactions: A review. Applied Catalysis A-General 2021; 626:118362, 12 pages.

SPIES LL, VERHOOG NJD, LOUW A. Acquired Glucocorticoid Resistance Due to Homologous Glucocorticoid Receptor Downregulation: A Modern Look at an Age-Old Problem. Cells 2021; 10:2529, 27 pages.

STOFBERG ML, CAILLET C, DE VILLIERS M, ZININGA T. Inhibitors of the Plasmodium falciparum Hsp90 towards Selective Antimalarial Drug Design: The Past, Present and Future. Cells 2021; 10:2849, 31 pages.

SWART AC, DU TOIT T, GOURGARI E, KIDD M, KEIL M, FAUCZ FR, STRATAKIS C. Steroid hormone analysis of adolescents and young women with polycystic ovarian syndrome and adrenocortical dysfunction using UPC2-MS/MS. PEDIATRIC RESEARCH 2021; 89:118-126.

UYS L, HOFMEYR JS, ROHWER JM. Coupling kinetic models and advection-diffusion equations. 1. Framework development and application to sucrose translocation and metabolism in sugarcane. in silico Plants 2021; 3(1):art. no. diab013, 18 pages.

UYS L, HOFMEYR JS, ROHWER JM. Coupling kinetic models and advection-diffusion equations. 2. Sensitivity analysis of an advection-diffusion-reaction model. in silico Plants 2021; 3(1):art. no. diab014, 14 pages.

VAN DER MERWE PDW, COTTERILL FPD, KANDZIORA M, WATTERS BR, NAGY B, GENADE T, FLUGEL T, SVENDSEN D, BELLSTEDT DU. Genomic fingerprints of palaeogeographic history: The tempo and mode of rift tectonics across tropical Africa has shaped the diversification of the killifish genus Nothobranchius (Teleostei: Cyprinodontiformes). Molecular Phylogenetics and Evolution 2021; 158:106988, 21 pages.

VAN NIEKERK DD, OOSTHUIZEN MM, DU TOIT F, SNOEP JL. Estimating merozoite release number and reinvasion efficiency in Plasmodium falciparum cell culture. Transactions of the Royal Society of South Africa 2021; 76(2):147-155.

VAN RENSBURG W, LAUBSCHER WE, RAUTENBACH M. High throughput method to determine the surface activity of antimicrobial polymeric materials. MethodsX 2021; 8:101593, 13 pages.

VAN SCHALKWYK FJ, STANDER MA, NSIZWANE M, MATHEE A, VAN WYK B-E. Fatal pyrrolizidine alkaloid poisoning of infants caused by adulterated Senecio coronatus. FORENSIC SCIENCE INTERNATIONAL 2021; 320:110680, 7 pages.

VERMEULEN RR, DEANE SM, DICKS LMT, ROHWER JM, VAN STADEN ADP. Manganese Privation-Induced Transcriptional Upregulation of the Class IIa Bacteriocin Plantaricin 423 in Lactobacillus plantarum Strain 423. Applied and Environmental Microbiology 2021; 87(21):e00976-21, 15 pages.

YILDIZ M, ISIK E, ABALI ZY, KESKIN M, OZBEK MN, BAS F, UCAKTURK SA, BUYUKINAN M, ONAL H, KARA C, STORBECK K, ET AL. Clinical and Hormonal Profiles Correlate With Molecular Characteristics in Patients With 11β-Hydroxylase Deficiency. Journal of Clinical Endocrinology and Metabolism 2021; 106(9):e3714-e3724.

Journal Articles (non-subsidised)

WEBER A, BELLSTEDT DU, MÖLLER M. Die Gesneriaceen Afrikas und ihre vogelblütigen Vertreter: Streptocarpus dunnii und S. myoporoides. Der Palmengarten 2021; 85:124-137.

Chapters in Books

ZININGA T, BÖTTGER E, MULTHOFF G. Role of Heat Shock Proteins in Immune Modulation in Malaria. In: Shonhai A, Picard D, Blatch GL (eds.) Heat Shock Proteins of Malaria, Advances in Experimental Medicine and Biology, Springer Nature, Switzerland, 2021: 169-186.​