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The Department of Physiological Sciences undertakes investigative research to better understand the health challenges facing South Africa. We have several research groupings headed up by excellent principal investigators who tackle a variety of disease states and aspects of regenerative medicine. The rationale is to gain a deeper understanding of the underlying mechanisms that drive the onset of pathophysiologic states, with the ultimate aim of designing novel therapeutic interventions.

Our laboratories are arguably the best equipped in our field within the South African context. For example, within our department we house the Central Analytical Facility (CAF) Microscopy Unit that contains state of the art fluorescence microscopes. The animal housing facility is also located within our precinct and is successfully managed by highly qualified staff members of our department. We also house the DST/NRF South African Research Chair for Integrative Skeletal Muscle Physiology, Biology and Biotechnology. 

Our dynamic vision means that we have successfully developed collaborative projects with several laboratories within South Africa and abroad. Colloquially this comprehensive strategic approach ensures the generation of first-class research outputs and the nurturing and development of human resources (students and staff), thereby further strengthening our national and international image within the Physiology discipline.

Please see below all our different  research groups, principal investigators and links to more information regarding each group, as well as information on our two Spin-out companies:

Research groups 

Principal Investigators

For more information

Cardio-Oncology Research group
​​Dr B Sishi

Cardio-Oncology Research gr​oup

Muscle Research group
​Prof K Myburgh

​​​Muscle Research group

​Cardio-Metabolic Research gro​​up
Dr Danzil Joseph ​

Research Group

​Cardiac Conduction Group

Dr Carin De Villiers

Cardiac Conduction Group​​​

Neuro Research group
​Prof B Loos

​​​​​​Neuro Rese​arch group

Cancer Research group
​Prof A-M Engelbrecht

​Cancer Research group

Bio-Inspired Drug Delivery (BioIDD) Research group​
Dr ​Sanjeev Rambharose​

Bio-Inspired Drug Delivery
(BioIDD) Research Group​

Integrated Metabolic Research group
​Dr T Nell

Integrated Me​tabolic Research Group ​(IMRG)​

Clinical Hemorheology and Coagulation group
​Prof R Pretorius

Clinical Hemorheology and Coagulation group


​​Spin-out companies