Dr Carin De Villiers
This group focuses on electrical abnormalities of the heart. Disorders of the cardiac conduction system, often identified by characteristic features on the electrocardiogram (ECG), predispose affected individuals to cardiac events including syncope, cardiac arrest and, in the worst case, sudden cardiac death. This research takes a closer look at specialised proteins and processes that are key for a rhythmical heartbeat. We use a wide variety of molecular techniques in different cellular models including human induced pluripotent stem cell (iPSC) derived cardiomyocytes.