Virology
Welcome to Stellenbosch University

Division of Medical Virology

​​​​​​​​​​Research

Publications (2007-2014)

2014

Journal Articles

 

BURGER, M.C., DEMPERS, J.J. & DE BEER, C., 2014. Profiling the approach to the investigation of viral infections in cases of sudden unexpected death in infancy in the Western Cape Province, South Africa. Forensic Science International, 239, pp.27–30. FSIjournal

VICTOR MAX CORMAN, NDAPEWA LAUDIKA ITHETE, LEIGH ROSANNE RICHARDS, M. CORRIE SCHOEMAN, WOLFGANG PREISER, CHRISTIAN DROSTEN AND JAN FELIX DREXLER,2014. Rooting the phylogenetic tree of MERS-Coronavirus by characterization of a conspecific virus from an African Bat. Journal of Virology. JVI

HAYLEY IPP, BONGANI B NKAMBULE, TIMOTHY D REID, DALENE DE SWARDT, LINDA-GAIL BEKKER, RICHARD H GLASHOFF., 2014. CD4+ T cells in HIV infection show increased levels of expression of a receptor for vasoactive intestinal peptide, VPAC2. Immunologic Research, pp.1–5. Immunol res

HAYLEY IPP, ANNALISE E ZEMLIN, RAJIV T ERASMUS, RICHARD H GLASHOFF., 2014. Role of inflammation in HIV-1 disease progression and prognosis. Critical Reviews in Clinical Laboratory Sciences, 51(2), pp.98–111. Pubfacts

GRAEME BRENDON JACOBS, EDUAN WILKINSON, SHAHIEDA ISAACS, GEORGINA SPIES, TULIO DE OLIVEIRA, SORAYA SEEDAT, SUSAN ENGELBRECHT, 2014. HIV-1 Subtypes B and C Unique Recombinant Forms (URFs) and Transmitted Drug Resistance Identified in the Western Cape Province, South Africa. PLoS ONE, 9(3), p.e90845. PLoS

JUSTEN MANASA, RICHARD LESSELLS, THERESA ROSSOUW, KEVINDRA NAIDU, CLOETE VAN VUUREN, DOMINIQUE GOEDHALS, GERT VAN ZYL, ARMAND BESTER, ANDREW SKINGSLEY, KATHARINE STOTT, SIVA DANAVIAH, TERUSHA CHETTY, LAVANYA SINGH, PRAVI MOODLEY, COLLINS IWUJI,  NUALA MCGRATH, CHRISTOPHER J. SEEBREGTS AND TULIO DE OLIVEIRA, 2014. Southern African Treatment Resistance Network (SATuRN) RegaDB HIV drug resistance and clinical management database: supporting patient management, surveillance and research in southern Africa. Database , 2014 .Database

​MOYO SIKHULILE, LECUYER TESSA, WANG RUI, GASEITSIWE SIMANI, WENG JIA, MUSONDA ROSEMARY, BUSSMANN HERMANN, MINE MADISA, ENGELBRECHT SUSAN, MAKHEMA JOSEPH, MARLINK RICHARD, BAUM MARIANNA K., NOVITSKY VLADIMIR, AND ESSEX M., 2014. Evaluation of the false recent classification rates of multiassay algorithms in estimating HIV type 1 subtype C incidence. AIDS Research and Human Retroviruses, 30(1), pp.29–36. ARHR

MTHEMBU Y., LOTZ Z., TYLER M., DE BEER C., RODRIGUES J., SCHOEMAN L. AND  MALL A., 2014. Purified Human Breast Milk MUC1 and MUC4 Inhibit Human Immunodeficiency Virus. Neonatology, 105(3), pp.211–217. KARGER

HOWARD NEWMAN, LUKAS BREUNIG, GERT VAN ZYL, AUGUST STICH AND WOLFGANG PREISER, 2014. A qualitative PCR minipool strategy to screen for virologic failure and antiretroviral drug resistance in South African patients on first-line antiretroviral therapy. Journal of Clinical Virology, 60(4), pp.387–391. JCV

REIKIE, BRIAN A., ADAMS, ROZANNE C. M.,  LELIGDOWICZ, ALEKSANDRA.,  HO, KEVIN., NAIDOO, SHALENA., RUCK, CANDICE E., DE BEER, CORENA., PREISER, WOLFGANG.,  COTTON, MARK F., SPEERT, DAVID P., ESSER, MONIKA., KOLLMANN, TOBIAS R.,2014. Altered Innate Immune Development in HIV-Exposed Uninfected Infants. JAIDS Journal of Acquired Immune Deficiency Syndromes, 66(3). JAIDS

PETER T. WITKOWSKIA,  BORIS KLEMPAA, NDAPEWA L. ITHETE, BRITA AUSTEA, JOHN K.E. MFUNED, JULIA HOVEKAD, SONJA MATTHEEE, WOLFGANG PREISER, DETLEV H. KRUGERA.,2014. Hantaviruses in Africa. Virus Research, 187(0), pp.34–42. Science Direct

2013

Journal Articles

 

ANDERSSON MI, MAPONGA T, IJAZ S, BARNES JM, THERON GB, MEREDITH SA, PREISER W, TEDDER RS. The epidemiology of hepatitis B virus infection in HIV-infected and HIV-uninfected pregnant women in the Western Cape, South Africa. Vaccine 2013; 31: 5579-5584. PubMed

ANDERSSON MI, PREISER W, MAPONGA T, HEYS I, TALJAARD JJ, VAN RENSBURG CJ, TEDDER RS, IJAZ S. Immune reconstitution hepatitis E: a neglected complication of antiretroviral therapy in Africa?. Aids 2013; 27: 487-492. PubMed

BOYLES TH, BAMFORD CM, BATEMAN K, BLUMBERG L, DRAMOWSKI A, KARSTAEDT A, KORSMAN S, LE ROUX DM, MAARTENS G, MADHI S, NAIDOO R, NUTTALL J, REUBENSON G, TALJAARD J, THOMAS J, VAN ZYL G, VON GOTTBERG , WHITELAW A, MENDELSON M. Guidelines for the management of acute meningitis in children and adults in South Africa. Southern African Journal of Epidemiology and Infection 2013; 28(1): 5-15. SAJEI

FREEMAN N, NEWMAN H. Shigella Keratitis in an HIV-exposed infant. Paediatric Infectious Disease Journal 2013; 32(4): 426-427. PubMed

GOLDSTONE SE, JESSEN H, PALEFSKY JM, GIULIANO AR, EDSON D, MOREIRA C, VARDAS E, ARANDA C, FERRIS DG, COUTLEE F, MARSHALL S, VUOCOLO S, HAUPT RM, GURIS D, GARDNER EM. Quadrivalent HPV vaccine efficacy against disease related to vaccine and non-vaccine HPV types in males. Vaccine 2013; 31: 3849-3855. PubMed

HOSSEINIPOUR MC, GUPTA RK, VAN ZYL G, ERON JJ, NACHEGA JB. Emergence of HIV drug resistance during first- and second-line antiretroviral therapy in resource-limited settings. Journal of Infectious Diseases 2013; 207(S2): S49-S56. PubMed

IPP H, ZEMLIN AE, GLASHOFF RH, VAN WYK J, VANKER N, REID T, BEKKER L. Serum adenosine deaminase and total immunoglobulin G correlate with markers of immune activation and inversely with CD4 counts in asymptomatic, treatment-naive HIV infection. Journal of Clinical Immunology 2013; 33: 605-612. PubMed

ITHETE NL, STOFFBERG S, CORMAN VM, COTTONTAIL VM, RICHARDS LR, SCHOEMAN MC, DROSTEN C, DREXLER JF, PREISER W. Close relative of Human Middle East respiratory syndrome Coronavirus in Bat, South Africa. Emerging Infectious Diseases 2013; 19(10): 1697-1699. PubMed

KABUE J-P, DE SWARDT D, DE BEER C, GLASHOFF RH. Short-Term antiretroviral therapy fails to reduce the expanded activated CCR5-Expressing CD4+ T Lymphocyte population or to restore the depleted naive population in chronically HIV-Infected individuals with active Pulmonary Tuberculosis. Aids Research and Human Retroviruses 2013; 29(5): 769-777. PubMed

MARITZ J, VAN ZYL GU, PREISER W. Irreproducible positive results on the Cobas Ampliperp/Cobas TaqMan HIV-1 Quality test are different qualitatively from confirmed positive results. Journal of Medical Virology 2013; 10.1002: 1-6. PubMed

NEWMAN H, GOODING C. Viral ocular manifestations: a broad overview. Reviews in Medical Virology 2013; 10.1002: rmv.1749. PubMed

PETERSEN DC, LIBIGER O, TINDALL EA, HARDIE R, HANNICK LI, GLASHOFF RH, MUKERJI M, FERNANDEZ P, HAACKE W, SCHORK NJ, HAYES VM. Complex patterns of genomic admixture within Southern Africa. PloS Genetics 2013; 9(3): 1-17. PubMed

PREISER W. Pooled HIV-1 viral load testing using dried blood spots to reduce the cost of monitoring antiretroviral treatment in a resource-limited setting. JAIDS-Journal of Acquired Immune Deficiency Syndromes 2013; 64(2): 134-137. PubMed

REIKIE B, NAIDOO S, RUCK CE, SLOGROVE A, DE BEER C, LA GRANGE H, ADAMS RC, HO K, SMOLEN K, SPEERT D, COTTON MF, PREISER W, ESSER M, KOLLMANN TR. Antibody responses to vaccination among South African HIV-exposed and unexposed uninfected infants during the first 2 years of life. Clinical and Vaccine Immunology 2013; 20(1): 33-38. PubMed

RENSBURG MA, ESSER M, DE BEER C. The seroprevalence of Bordetella pertussis antibodies in adolescents in the Western Cape. Southern African Journal of Epidemiology and Infection 2013; 28(4): 202-206. SAJEI

TANG MW, RHEE S-Y, BERTAGNOLIO S, FORD N, HOLMES S, SIGALOFF KC, HAMERS RL, DE WIT TFR, FLEURY HJ, KANKI PJ, RUXRUNGTHAM K, HAWKINS CA, WALLIS C, STEVENS WS, VAN ZYL GU. Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line Stavudine-containing antiretroviral therapy: Programmatic implications for countries phasing out Stavudine. Journal of Infectious Diseases 2013; Suppl 2: S70-S77. PubMed

VAN SCHALKWYK M, ANDERSSON MI, ZEIER MD, LA GRANGE M, TALJAARD JJ, THERON GB. The impact of revised PMTCT guidelines: A view from a public sector ARV clinic in Cape Town, South Africa. JAIDS-Journal of Acquired Immune Deficiency Syndromes 2013; 63(2): 234-238. PubMed

VAN ZYL GU, LIU S, CLAASSEN M, ENGELBRECHT S, DE OLIVEIRA T, PREISER W, WOOD NH, TRAVERS S, SHAFER RW. Trends in Genotypic HIV-1 antiretroviral resistance between 2006 and 2012. PloS ONE 2013; 8(6): e67188. PubMed

​NDEBIA EJ, TCHOKONTE-NANA V, UMAPATHY E, TAMADJOU TCHUEN CR. Anti-ulcerogenic properties of Albuca setosa. Journal of Medicinal Plants Research 2013; 7(47): 3420-3426. JMPR

Doctoral projects completed

ITHETE NLInvestigation of small mammal-borne viruses with zoonotic potential in South Africa. PhD, 2013. 200 pp. Promotor: Preiser W.

WILKINSON EOrigin and phylodynamics of HIV-1 subtype C in South Africa. PhD, 2013. 284 pp. Promotor: Engelbrecht S.

Masters Projects completed​

MARITZ JIrreproducible positive results on the Cobas ampliperp/Cobas TaqMan HIV-1 Quality test are different qualitatively from confirmed positive results. MMed, 2013. 6 pp. Studieleier: Van Zyl GU. Medestudieleier: Preiser W.

LOOTS SErythrocyte apoptosis (erythroptosis) and anaemia in chronic HIV-1 infection: relationship with immune activation and viraemia. MScGeneeskWet, 2013. 89 pp. Studieleier: Glashoff RH. Medestudieleier: Ipp H.


2012

Journal Articles

 

ANDERSSON MI, LOW N, IRISH CJ, VERLANDER NQ, CARRINGTON D, HORNER P, STUART JM, HICKMAN M. Investigation of a large community-based outbreak of hepatitis B infection in the United Kingdom. Epidemiology and Infection 2012; 140: 47-57. PubMed

ANDERSSON MI, MAPONGA T, IJAZ S, THERON GB, PREISER W, TEDDER RS. High HBV viral loads in HIV-infected pregnant women at a tertiary hospital, South Africa. JAIDS-Journal of Acquired Immune Deficiency Syndromes 2012; 60(4): 111-112. PubMed

BROWN B, BUDNIK P, DE SWARDT G, DUBY Z, GEFFEN N, KANYEMBA B, MCINTYRE J, MYER L, SCHEIBE A, SCHOWALTER L, SONDERUP M, SPEARMAN W, TOLEDO C, TUCKER T, VAN DYK R, VAN ZYL GU. Southern African guidelines for the safe use of pre-exposure prophylaxis in men who have sex with men who are at risk for HIV infection. Southern African Journal of HIV Medicine 2012; 13(2): 40-55. SAJHIV

CONRADIE F, WILSON D, BASSON A, DE OLIVEIRA T, HUNT G, JOEL D, PAPATHANASOPOULOS MA, PREISER W, KLAUSNER J, SPENCER D, STEVENS WS, VENTER F, VAN VUUREN C, LEVIN L, MEINTJIES G, ORRELL C, SUNPATH H, ROSSOUW T, VAN ZYL GU. The 2012 southern African ARV drug resistance testing guidelines. Southern African Journal of HIV Medicine 2012; 13(4): 162-167.SAHIVSoc

FISHER R, VAN ZYL GU, TRAVERS SAA, KOSAKOVSKY POND SL, ENGELBRECH S, MURRELL B, SCHEFFLER K, SMITH D. Deep Sequencing reveals minor protease resistance mutants in patients failing a protease inhibitor regimen. Journal of Virology 2012; 86(11): 1-8. PubMed

GIULIANO AR, PALEFSKY JM, GOLDSTONE S, MOREIRA ED, VARDAS E, ARANDA C, JESSEN H, FERRIS DG, COUTLEE F, MARSHALL BG, VUOCOLO S, HAUPT RM, GURIS D. Immunogenicity of the quadrivalent Human Papillomavirus (Type 6/11/16/18) vaccine in males 16 to 26 years old. Clinical and Vaccine Immunology 2012; 19(2): 261-267. PubMed

JACOBS GB, BOCK S, SCHUCH A, MOSCHALL R, SCHROM E-M, ZAHN J, REUTER C, PREISER W, RETHWILM A, ENGELBRECHT S, KERKAU T, BODEM J. Construction of a high titer infectious HIV-1 subtype C proviral clone from South Africa. Viruses-Basel 2012; 4: 1830-1843. PubMed

MALNATI MS, HELTAI S, COSMA A, REITMEIR P, ALLGAYER S, GLASHOFF RH, LIEBRICH W, VARDAS E, IMAMI N, WESTROP S, NOZZA S, TAMBUSSI G, BUTTO S, FENALES-BELASIO E, ENSOLI B, ENSOLI F, TRIPICIANO A, FORTIS C, LUSSO P, POLI G, ERFLE V, HOLMES H. A new antigen scanning strategy for monitoring HIV-1 specific T-cell immune responses. Journal of Immunological Methods 2012; 375: 46-56. PubMed

MARITZ J, PREISER W, VAN ZYL GU. Establishing diagnostic cut-off criteria for the COBAS AmpliPrep/COBAS TaqMan HIV-1 qualitative test through validation against the Amplicor DNA test v1.5 for infant diagnosis using dried blood spots. Journal of Clinical Virology 2012; 53: 106-109. JCV

PEACOCKE J, LOTZ ZE, DE BEER C, ROUX P, MALL AS. The role of crude saliva and purified salivary mucins in the inhibition of the Human Immunodeficiency virus type 1. Virology Journal 2012; 9(177): 1-9. PubMed

REIKIE BA, ADAMS RCM, RUCK CE, HO K, LELIGDOWICZ A, PILLAY S, NAIDOO S, FORTUNO ES, DE BEER C, PREISER W, COTTON MF, SPEERT DP, ESSER M, KOLLMANN TR. Ontogeny of Toll-Like receptor mediated Cytokine responses of South African infants throughout the first year of life. PLoS ONE 2012; 7(9): 1-11. PubMed

SLOGROVE A, REIKIE B, NAIDOO S, DE BEER C, HO K, COTTON MF, BETTINGER J, SPEERT D, ESSER M, KOLLMANN TR. HIV-Exposed Uninfected Infants are at Increased Risk for Severe Infections in the First Year of Life. . Journal of Tropical Paediatrics 2012; 58(6): 505-508. PubMed

VARDAS E, STANESCU I, LEINONEN M, ELLEFSEN K, PANTALEO G, VALTAVAARA M, USTAV M, REIJONEN K. Indicators of therapeutic effect in FIT-06, a phase II trial of a DNA vaccine, GTU-multi-HIVB, in untreated HIV-1 infected subjects. Vaccine 2012; 30(27): 4046-4054. PubMed

ANDERSSON MI, VAN RENSBURG CJ. The management of hepatitis C virus infection in difficult-to-treat populations: patients with end stage renal disease, HIV infected patients and children. The South African Gastroenterology Review 2012; 10(1): 27-31. SABINET

DE BEER C, ESSER M, PREISER W. Optimising automation of a manual enzyme-linked immunosorbent assay. Afr J Lab Med 2012: 1-3. AJLM

KOZISEK M, HENKE S, SASKOVA KG, JACOBS GB, SCHUCH A, BUCHHOLZ B, MULLER V, KRAUSSLICH H-G, REZACOVA P, REZACOVA P, KONVALINKA J, BODEM J. Mutations in HIV-1 gag and pol compensate for the loss of viral fitness caused by a highly mutated protease. Antimicrobial Agents and Chemotherapy 2012; 56(8): 4320-4330. PubMed

MURRELL B, SHERWARD DJ, WILLIAMSON C. Degenerate primer IDs and the birthday problem. Proceedings of the National Academy of Sciences of the United States of America 2012; 109(21): 1330. PubMed

​Doctoral Projects completed

​VAN ZYL GU. The investigation of genotypic antiretroviral drug resistance in the context of the South African national antiretroviral roll-out programme. PhD, 2012. 60 pp. Promotor: Preiser W. Medepromotor: Nachega JB.

Masters Projects completed

​CHOTUN BN. The Prevalence of Hepatitis B virus infection in an HIV-Exposed paediatric cohort from the Western Cape, South Africa. MScGeneeskWet, 2012. 125 pp. Studieleier: Van Zyl GU.

MAPONGA T. An investigation of hepatitis B virus in antenatal women tested for human immunodeficiency virus, in the Western Cape Province of South Africa. MScGeneeskWet, 2012. 89 pp. Studieleier: Andersson MI. Medestudieleier: Preiser W.

MAREE L. Investigating the aetiology of respiratory tract infections in children admitted to Tygerberg Children's Hospital using molecular methods and viral culture. MMed, 2012. 103 pp. Studieleier: Van Zyl GU.

NKAMBULE B. Platelet Flow Cytometry and coagulation tests as markers of immune activation in chronic HIV infection. MScGeneeskWet, 2012. 112 pp. Studieleier: Glashoff RH.

SELEKA M. Development of selective real-time PCR (SPCR) assays for the detection of K103N resistance mutation in minor HIV-1 populations. MScGeneeskWet, 2012. 137 pp. Studieleier: Engelbrecht S. Medestudieleier: Van Zyl GU.

​General Presentations

CHOTUN BN, ANDERSSON MI, IJAZ S, COTTON MF, NEL E, TEDDER RS, PREISER W. Prevalence of HBV Infection in a cohort of HIV-Exposed Infants from the Western Cape, South Africa. 56th Annual Academic Day, University of Stellenbosch, August 2012.

DE BEER C. Project Progress, Sample Collection and Technology Transfer. 7th Annual GHRC / CAVD Meeting. Washington, USA, December 2012.

ENGELBRECHT S, CLAASSEN M, WILKINSON E, JACOBS GB, VAN ZYL GU, DE OLIVEIRA T AND PREISER W. Detection of unique HIV-1 recombinant forms in South Africa: is the HIV-1 subtype C epidemic changing? AIDS 2012, XIX International AIDS Conference, July 2012, Washington DC USA.

ENGELBRECHT S, CLAASSEN M, WILKINSON E, JACOBS GB. Detection of unique HIV-1 recombinant forms in South Africa - is the HIV-1 subtype C epidemic changing? XIX International AIDS Conference, Washington, USA, July 2012.

FISHER R, VAN ZYL GU, TRAVIS S, POND SLK, ENGELBRECHT S, MURRELL B, SCHEFFLER K, SMITH D. Deep sequencing reveals minor protease resistance mutations in patients failing a protease inhibitor regimen. IRTG 1522 annual symposium, Wurzburg, Germany, June 2012.

HART D, MOELICH A, VAN ZYL GU. Preparation of a quantitative and stable respiratory syncytial virus standard for optimisation of molecular assays.

JACOBS GB. Construction and characterization of infectious HIV-1 subtype C proviral molecular clones. IRTG 1522 annual symposium, Wurzburg, Germany, June 2012.

JACOBS GB. Construction and characterization of infectious HIV-1 subtype C proviral molecular clones. 56th Annual Academic Day, University of Stellenbosch, August 2012.

JACOBS GB. Construction and characterization of infectious HIV-1 subtype C proviral molecular clones. Postdoctoral Research Day, University of Stellenbosch, November 2012.

JACOBS GB. HIV-1 evolution and recombination in South Africa. Presented at the International Research training group (IRTG 1522) International Meeting of HIV and associate infectious diseases. Wurzburg, Germany, January 2012.

JACOBS GB. HIV-1 resistance analyses from therapy-naïve patients in South Africa. Clinical Haematology, Tygerberg Hospital, February 2012.

LA GRANGE H, ESSER M, DE BEER C. Measles virus IGG levels in exposed uninfected (HEU) and HIV unexposed (UE) babies in response to routine vaccination. International African Vaccinology Conference, Cape Town, November 2012.

LOOTS S, DE SWARDT D, IPP H, GLASHOFF RH. Increased anaemia-associated erythrocyte apoptosis (erythroptosis) in chronic HIV infection: relationship with immune activation and oxidative stress. 56th Annual Academic Day, University of Stellenbosch, August 2012.

NKAMBULE B, IPP H, GLASHOFF RH. Platelet flow cytometry and markers of immune activation in asymptomatic, treatment naïve HIV infection. European Haematology Association (EHA) Conference, Amsterdam, Netherlands, June 2012.

POOVAN K, DE SWARDT D, IPP H, GLASHOFF RH. Decreased responsiveness of monocytes to LPS in chronic hiv-1 infection as detected utilizing an optimized whole blood LPS stimulation assay. 56th Annual Day, University of Stellenbosch, August 2012.

REDDY K. MRC Early Career Scientist conference. MRC, Cape Town, Oct 2012.

REID TD, IPP H, GLASHOFF RH. Ex Vivo characterization of markers of B-Cell activation, exhaustion and apoptosis in asymptomatic HIV-infected individuals. 56th Annual Academic Day, University of Stellenbosch, August 2012.

VAN ZYL GU, CLAASSEN M, ENGELBRECHT S, DE OLIVEIRA T, PREISER W, WOOD NH, TRAVERS SAA, SCHAEFER M. Changing patterns of NRTI and PI resistance mutations between 2006 and 2011 in >1,200 ART-experienced South African patients: association with the introduction of tenofovir (TDF) and abacavir (ABC) and with the cumulative effects of LPV/r therapy. AIDS 2012, XIX International AIDS Conference, July 2012, Washington DC USA.

 

2011

Journal Articles

 

ENGELBRECHT S, WILKINSON E, DE OLIVEIRA T. Diversity and molecular epidemiology of HIV-1 in Cape Town; 1984 to 2010. Retrovirology 2011; 8(Suppl 2): 21. Retrovirology

JONES CE, NAIDOO S, DE BEER C, ESSER M, KAMPMANN B, HESSELING C. Maternal HIV Infection and Antibody Responses Against Vaccine-Preventable Diseases in Uninfected infants. Jama-Journal of the American Medical Association 2011; 305(6): 576-584. PubMed

KASANG C, KALLUVYA S, MAJINGE C, STICH A, BODEM J, KONGOLA G, JACOBS G, MILDNER M, HENSEL I, HORN A, PREISER W, VAN ZYL GU, RETHWILM A. HIV Drug Resistance (HIVDR) in Antiretroviral Therapy-Naïve Patients in Tanzania Not Eligible for WHO Threshold HIVDR Survey is Dramatically High. PloS ONE 2011; 6(8): 1-11.PubMed

MARITZ J, PREISER W. Cost-Effectiveness of Nucleic Acid Amplification Tests for Identifying Acute HIV Infections. Journal of Clinical Microbiology 2011; 49(4): 1704. PubMed

OYARO M, MBITHI J, OYUGI F, LATEN A, ANZALA O, ENGELBRECHT S. Molecular Characterization of HIV Type 1 Among HIV-Infected Respondents in a Cohort Being Prepared for HIV Phase III Vaccine Clinical Trials, Western Kenya. Aids Research and Human Retroviruses 2011; 27(3): 257-264. ARHR

SOLOMONS R, SLOGROVE A, SCHOEMAN JF, MARAIS BJ, VAN ZYL GU, MARITZ JS, VAN TOORN R. Acute Extrapyramidal Dysfunction in Two HIV-infected children. Journal of Tropical Paediatrics 2011; 57(3): 227-231.PubMed

VAN ZYL GU, RABIE H, NUTTAL J, COTTON MF. It is time to consider third-line options in antiretroviral-experienced paediatric patients? BMC Medicine 2011; 14: 55-62. PubMed

VAN ZYL GU, VAN DER MERWE L, CLAASSEN M, ZEIER MD, PREISER W.

Antiretroviral Resistance Patterns and Factors Associated with Resistance in Adult Patients Failing NNRTI-Based Regimens in the Western Cape, South Africa. Journal of Medical Virology  2011; 83: 1764-1769. PubMed

VAN ZYL GU, VAN MENS TE, MCILLERON H, ZEIER MD, NACHEGA JB, DECLOEDT E, MALAVAZZI C, SMITH P, HUANG Y, VAN DER MERWE L, GANDHI M, MAARTENS G. Low lopinavir plasma or hair concentrations explain second-line protease inhibitor failures in a resource-limited setting. JAIDS-Journal of Acquired Immune Deficiency Syndromes 2011; 56(4): 333-339. JAIDS

VARDAS E, GOLDSTONE S, PALEFSKY JM, MOREIRA ED, PENNY ME, ARANDA C, JESSEN H, MOI H, FERRIS K-L. External Genital Human Papillomavirus Prevalence and Associated Factors among Heterosexual men on 5 Continents. Journal of Infectious Diseases 2011; 203: 58-65. PubMed

CHARMAN A, WALZL G, PREISER W. The Capacity of African Research Institutions to Respond to HIV/M.tuberculosis Co-Infection. The Open Infectious Diseases Journal, 1874-2793/11 2011; 5(Suppl-1-M6): 60-80. Open Infect Dis J

NACHEGA JB, MARCONI VC, VAN ZYL GU, GARDNER EM, PREISER W, HONG SY, MILLS EJ, GROSS R. HIV Treatment Adherence, Drug Resistance, Virologic Failure: Evolving Concepts. Infectious Disorders - Drug Targets; 1871-5265/11 2011; 11: 167-174. PubMed

Proceedings International

ADAMS RCM, COTTON MF, ESSER M, DE BEER C. Pilot study of the innate immune abnormalities in HIV exposed uninfected infants. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

AFRICA LD, ISAACS S, ENGELBRECHT S. Molecular Characterization of Unique HIV-1 BC recombinants. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

ANDERSSON MI. HBV vaccination in the era of HIV. Virology Africa 2011. Virology Africa 2011. V&A Waterfront, Cape Town, South Africa, 2011: 1.

ANDERSSON MI. The prevalence and character of HBV infection in HIV-infected and uninfected pregnant women in the Western Cape. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

ANDERSSON MI. The prevalence of HBV infection in HIV-exposed babies. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

CHOTUN BN, ANDERSSON MI, COTTON MF, PREISER W. A cross-sectional study of the prevalence of Hepatitis B virus infection in HIV-exposed infants at Tygerberg Hospital, Cape Town.

Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

DE SWARDT D, IPP H, GLASHOFF RH. Phenotypic characterization of Blood dendritic cells in chronically HIV-infected individuals in South Africa. Virology Africa 2011. Virology Africa Congress, V&A Waterfront, Cape Town, South Africa, 2011: 1.

ENGELBRECHT S, CLAASSEN M, VAN ZYL GU, PREISER W. Detection of unique HIV-1 recombinants in South Africa. 18th HIV Dynamics & Evolution, Ireland. 18th HIV Dynamics & Evolution, Radisson Blue Hotel & Spa, Galway, 2011: 73.

ENGELBRECHT S. Frequent detection of unique recombinants in South Africa. 5th SA AIDS Conference, Durban. 5th SA AIDS Conference, International Conference Centre, Durban, South Africa, 2011: 587.

FISHER R, ENGELBRECHT S, PREISER W, TRAVIS S, SMITH D, HAUBRICH R, SCHEFFLER K, VAN ZYL GU. Ultra deep pyrosequencing reveals minor variant evolution in HIV patients on therapy. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

IPP H, DE SWARDT D, GLASHOFF RH. The VIP receptor VPAC2 on CD4T cells as a novel marker of immune activation in HIV infection and potential target for immune modulation. 6th International AIDS Society (IAS) Conference on HIV Pathogenesis and treatment; 2011. 6th International AIDS Society (IAS) Conference on HIV Pathogenesis and treatment, Rome, Italy, 2011:1.

IPP H, GLASHOFF RH, ABAYOMI EA. Myeloperoxidase and MPXI as markers of inflammation in asymptomatic HIV-1 infection. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

ISAACS S, GLASHOFF RH, SEEDAT S, JOSKA J, ENGELBRECHT S. Molecular characterization of tat: A possible mediator of HIV-1 associated dementia (HAD). Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

ITHETE NL, MATTHEE CA, AUSTE B, KLEMPA B, WITKOWSKI P, PREISER W. Evidence of Hantavirus infection in South Africa. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

​LA GRANGE H, ESSER M, DE BEER C. Measles virus IgG levels in response to routine vaccines in HIV exposed uninfected (HEU) and HIV unexposed (EU) infants. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

LOOTS S, DU PLESSIS M, JOOSTE AEC, IPP H, GLASHOFF RH. Erythrocytes apoptosis (Erythroptosis) and Anaemia in chronic HIV infection: Relationship with immune activation, Oxidative stress and Viraemia. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

MAPONGA T, ANDERSSON MI, THERON GB, PREISER W. Cross sectional analysis of the prevalence and character of Hepatitis B virus infection in HIV infected and HIV uninfected pregnant women in the Western Cape. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

NAIDOO S, ESSER M, IPP H, DE BEER C. Longitudinal investigation of vaccine specific antibody levels and surrogate markers of adaptive immune responses in HIV exposed uninfecte4d (HEU) and unexposed (UE) infants. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

SAMPSON N, PREISER W. Novel positive controls for viral immunohistochemistry. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

VAN ZYL GU, PREISER W. Antiretroviral drug resistance poses more challenges in children than in adults Western Cape resistance data 2007-2010. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

VAN ZYL GU. "To test of not to Test?" That is the question: A Southern African perspective on ART failure monitoring. 6th South African HIV&TB Drug Resistance and Treatment Monitoring Workshop. 6th South African HIV&TB Drug Resistance and Treatment Monitoring Workshop, University of Botswana, Gaborone, Botswana, 2011: 1.

VAN ZYL GU. Protagonist: Genotyping and a 3rd line therapy option must be available in the state Sector. In: Treatment of HIV- the changing face of ART in 2011. FIDSSA 2011. 8-11 July 2011. FIDSSA 2011, Durban, South Africa, 2011: 1.

VAN ZYL GU. South African HIV Clinicians Society: Paediatric Skills Building Workshop at the South African AIDS Conference. South African HIV Clinicians Society. 8 June 2011, 2011: 1.

​WILKINSON E, ENGELBRECHT S, DE OLIVEIRA T. Origin of the heterosexual subtype C HIV-1 epidemic in Southern Africa. Virology Africa 2011. Virology Africa 2011, V&A Waterfront, Cape Town, South Africa, 2011: 1.

WILKINSON E. History and Evolution of the Subtype C HIV-1 Epidemic in Southern Africa. 5th SA AIDS Conference, Durban. 5th SA AIDS Conference, International Convention Centre, Durban, South Africa, 2011: 125.

Proceedings National

ANDERSSON MI. HBV infection in the era of HIV. HBV Genotype Conference; September 2011. HBV Genotype Conference, 2011: 1.

​ANDERSSON MI. The prevalence and character of HBV infection HIV infected women at Tygerberg Hospital. FIDSSA. September 2011. FIDSSA 2011, Tygerberg Hospital, Cape Town, South Africa, 2011: 1.

​Doctoral Projects Completed

ROMANI B. Mutagenesis and functional studies of the HIV-1 vpr gene and vpr protein obtained from South African virus strains. Supervisors: Engelbrecht S; Glashoff RH. PhD, 2011. 100 pp. Promotor: Engelbrecht S. Medepromotor: Glashoff RH.

General Presentations

ADAMS A, BOUIC P, ESSER M, DE BEER C. Ontogeny of the innate immune response in a South African infant cohort. 55th Annual Academic Day, 2011.

ANDERSSON MI, PREISER W, THERON GB. Prevalence and characterization of HBV infection in HIV infected women. 55th Annual Academic Day, 2011.

FISHER R, PREISER W, ENGELBRECHT S, VAN ZYL GU. Ultra deep pyrosequencing reveals minor variant evolution in HIV patients on therapy. 55th Academic Day, 2011.

ISAACS S, GLASHOFF RH, ENGELBRECHT S. Molecular characterization and analysis of HIV-1 tat. 55th Annual Academic Day, 2011.

ITHETE NL, PREISER W, MATTHEE CA. Do Hantavirus infections occur in South Africa? 55th Annual Academic Day, 2011.

MARITZ J, VAN ZYL GU. Refining diagnostic HIV-1 PCR criteria for early infant diagnosis. 55th Annual Academic Day, 2011.

NAIDOO S, ESSER M, DE BEER C. Longitudinal investigation of vaccine specific antibody levels and surrogate markers of adaptive immune responses in HIV exposed uninfected infants. 55th Annual Academic Day, 2011.

REID TD, WIEHAHN A, ABAYOMI EA, GLASHOFF RH, IPP H. B-cell activation in chronic asymptomatic HIV infection: potential markers of immune activation. 55th Annual Academic Day, 2011.

SMITH K, DE BEER C, ESSER M. Pitfalls of portable rapid Haemoglobin testing: evaluation of heel prick method versus venous blood. 55th Academic Year Day, 2011.

VAN ZYL GU, PREISER W. Antiretroviral drug resistance poses more challenges in children than in adults: Western Cape resistance data 2007-2010. 55th Annual Academic Day, 2011.

​WILKINSON E, ENGELBRECHT S, DE OLIVEIRA T. Unusual transmission clusters of subtype C HIV-1 in a small cohort of heterosexual patients from Cape Town. 55th Annual Academic Day, 2011.


2010

Journal Articles


ANDERSSON MI, VAN ZYL GU, PREISER W, LANGENEGGER E, THERON GB. Pandemic flu (H1N1) 2009 and pregnancy. SAMJ South African Medical Journal 2010; 100(4): 192-194. SAMJ

COTTON MF, RABIE H, VAN ZYL GU. Another Milestone in Minimizing Risks to Mothers Exposed to Single-Dose Nevirapine for Prevention of Vertical Transmission of HIV-1 to Infants: What Next? Clinical Infectious Diseases 2010; 50(6): 909-911 CID

COTTON MF, RABIE H, VAN ZYL GU. Antiretroviral Therapy in Children with Tuberculosis: Progress toward Defining the Issues. Journal of Infectious Diseases 2010; 201(8): 1113-1114.PubMed

DE SWARDT D, GLASHOFF RH. ARV fails to normalize the reduction of blood plasmacytoid and myeloid dendritic cells in HIV infected South African individuals with active TB. Aids Research and Human Retroviruses 2010; 26(10): 74. ARHR

HABTE HH, DE BEER C, LOTZ ZE, ROUX P, MALL AS. Anti-HIV-1 activity of salivary MUC5B and MUC7 mucins from HIV patients with different CD4 counts. Virology Journal 2010; 7(269): 1-9.Virologyj

MAREE L, VAN ZYL GU, LOTTER S L, DE BEER C, ESSER M, PREISER W. Young Age a Predictor of Weak Reactivity in a Rapid Antibody Test in Infants Infected With HIV. Journal of Medical Virology 2010; 82: 1314-1317. PubMed

MARITZ J, BENATAR M, DAVE JA, HARRISON TB, BADRI M, LEVITT N, HECKMANN JM. HIV Neuropathy in South Africans: frequency, characteristics and risk factors. Muscle & Nerve 2010; 1: 1-9. PubMed

MARITZ J, MAREE L, PREISER W. Pandemic influenza A (H1N1) 2009: the experience of the first six months. Clinical Chemistry and Laboratory Medicine 2010; 48(1): 11-21. PubMed

PAPATHANASOPOULOS MA, VARDAS E, WALLIS C, GLASHOFF RH, BUTTO S, POLI G, MALNATI MS, CLERICI M, ENSOLI B. Characterization of HIV Type 1 genetic diversity among South African participants enrolled in the AIDS vaccine integrated project (AVIP) study. Aids Research and Human Retroviruses 2010; 26(6): 1-5. ARHR

PREISER W. Klinik, Epidemiologie und diagnostik tropischer virusinfektionen. Pharmazie 2010; 39: 34-40. Pharmazie

RABENAU HF, LENNEMANN T, KIRCHER C, GURTLER L, STASZEWSKI S, PREISER W, MCPHERSON P, ALLWINN R, DOERR HW. Prevalence- and gender-specific immune response to opportunistic infections in HIV-infected patients in Lesotho. Sexually Transmitted Diseases 2010; 37(7): 454-459. PubMed

ROMANI B, ENGELBRECHT S, GLASHOFF RH. Functions of Tat: the versatile protein of human immunodeficiency virus type 1. Journal of General Virology 2010; 91: 1-12.PubMed

ROMANI B, GLASHOFF RH, ENGELBRECHT S. Functional integrity of naturally occurring mutants of HIV-1 subtype C vpr. Virus Research 2010; 153: 288-298. Science direct

VAN ZYL GU, COTTON MF, CLAASSEN M, ABRAHAMS C, PREISER W. Surveillance of transmitted resistance to antiretroviral drug classes among young children in the Western Cape Province of South Africa. Paediatric Infectious Disease Journal 2010; 29(3): 1-2. PubMed

VAN ZYL GU, KORSMAN SNJ, MAREE L, PREISER W. Nuclisens EasyQ HIV-1 V1.2 system: Detection of human plasma-derived background signal. Journal of Virological Methods 2010; 165: 318-319. PubMed

Proceedings International

​DE BEER C. HIV/AIDS Outreach in Africa – An all-in-one Mobile BSL-3 Health Unit which translates HIV Research from workbench to the clinic. 5th Annual CAVD Meeting. The Collaboration for AIDS Vaccine Discovery, The Hyatt Hotel, Washington, 2010: 0.

DE BEER C. Project Progress, Sample Collection and Technology Transfer. 5th Annual CAVD Meeting, The Collaboration for AIDS Vaccine Discovery, 2010: 0.

DE SWARDT D, GLASHOFF RH. Anti-retroviral (ARV) therapy fails to normalize the exacerbated reduction of blood plasmacytoid and myeloid dendritic cells (pDC and mDC) in HIV and TB co-infected South African individuals. AIDS Vaccine conference 2010, Atlanta, 2010: 0.

ENGELBRECHT S, MSIMANGA P, VARDAS E, GLASHOFF RH. HIV-1 recombinants identified in Mpumalanga and Eastern Cape Provinces of South Africa. 10th International Conference on Molecular Epidemiology and Evolutionary Genetics of Infectious Diseases (MEEGID X), Amsterdam, Netherlands, 2010: 0.

ENGELBRECHT S, MSIMANGA P, WILKINSON E, GLASHOFF RH, VARDAS E. HIV-1 recombinants in Mpumalanga Province, South Africa. 17th International HIV Dynamics and Evolution Conference, Pacific Grove, CA, USA, 2010: 0.

ROMANI B, GLASHOFF RH, ENGELBRECHT S. Functional integrity of naturally mutated forms of HIV-1 subtype C Vpr: comparison with subtype B and the consensus sequence of the protein. XVIII International AIDS Conference, Austria, 2010: 0.

SCHNEIDER JW, MOOLLA AY, JORDAAN HF, ENGELBRECHT S, MUNBODH R, WASSERMAN E. The value of polymerase chain reaction in the laboratory diagnosis of clinically suspected onychomycosis. XXVIIIth International Congress of the International Academy of Pathology, Transamerica Hotel Conference Centre, Sao Paulo, Brazil, Wiley-Blackwell 2010: 196-197.

WILKINSON E, DE OLIVEIRA T, ENGELBRECHT S. History and evolution of HIV-1 subtype C in Cape Town, South Africa. 16th International Bioinformatics Workshop on Virus Evolution and Molecular Epidemiology, Johns Hopkins University, Baltimore, Bethesda, 2010: 0.

MARITZ J, HENRICKSON R, ENGELBRECHT S, VAN ZYL GU. Development and optimization of a loop-mediated amplification (LAMP) assay for the detection of Human Immunodeficiency Virus subtype C strains. Oral presentation, EMBO Global Exchange Lecture Course, Stellenbosch, Western Cape.

Masters Projects completed

​ITHETE NL. Molecular identification and characterisation of Rodent- and Shrew-borne hantaviruses. MScGeneeskWet, 2010. 120 pp. Studieleier: Preiser W.

PILLAY S. Phenotypic and functional characterization of cytotoxic T lymphocytes in HIV infected South African adults. MScGeneeskWet, 2010. 135 pp. Studieleier: Glashoff RH.

General Presentations

​ADAMS R, ESSER M, DE BEER C. Innate immune abnormalities of South African HIV exposed and unexposed infants: 54th Annual Academic day, Tygerberg.

BURGER M, DEMPERS JJ, DE BEER C. Profiling the approach to the investigation of viral infections in cases of Sudden Unexpected Death in Infancy (SUDI) in the Western Cape Province: 54th Annual Academic day, Tygerberg.

BURGER M, DEMPERS JJ, DE BEER C. Profiling the approach to the investigation of viral infections in cases of Sudden Unexpected Death in Infancy (SUDI) in the Western Cape Province: FSASP (PATHVINE) Congress, Somerset West.

DE BEER C, NAIDOO S, STEENKAMP J, ESSER M. A pilot study of HIV exposed uninfected and unexposed infants in the Western Cape: SAIS Conference, Cradle of Humankind, Johannesburg.

DE BEER C. Some ethical considerations in animal research: 5th Academic day (SMLTSA) Pinelands.

ESSER M, COTTON MF, DE BEER C. The HIV exposed infant – not infected but affected: 54th Annual Academic day, Tygerberg.

IPP H, DE SWARDT D, GLASHOFF RH. The VIP receptor VPAC-2 as a novel marker of T cell activation in HIV and a potential target for immune modulation: South African Immunology Society (SAIS) Annual Congress, Johannesburg.

IPP H, GREWAL R, FORBES AN, GLASHOFF RH. A novel lymphocyte differential count as a cost-effective method in the assessment of immune activation in chronic HIV-infection: A Pilot Study: PATHVINE 2010, 50TH Annual Congress of the federation of South African Societies of Pathology (FSASP), Somerset West.

NAIDOO S, ESSER M, DE BEER C. Post-vaccine levels of specific antibodies in HIV-exposed uninfected and healthy infants: 54th Annual Academic day, Tygerberg.

SMIT K, ESSER M, DE BEER C. Pitfalls of portable rapid haemoglobin testing: 54th Annual Academic day, Tygerberg.

VAN WYK J, ZEMLIN AE, GLASHOFF RH. Serum ADA levels and CD26 expression as markers of generalized immune activation in chronic HIV infection: PATHVINE 2010, 50th Annual Congress of the federation of South African Societies of Pathology (FSASP), Somerset West.

MARITZ J, MOELICH A, PREISER W, VAN ZYL GU. Performance of the Cobas AmpliPrep/Cobas TaqMan HIV-1 Qualitative test in the diagnosis of HIV-1 in young children. Oral presentation, 54th Annual Academic Day of the Faculty of Health Sciences, University of Stellenbosch.


2009

Journal Articles


JACOBS GB, LOXTON AG, LATEN JD, ROBSON BA, JANSE VAN RENSBURG E, ENGELBRECHT S. Emergence Q1 and diversity of different HIV-1 subtypes in South Africa, 2000-2001. Journal of Medical Virology 2009; 81 : 1852-1859.
No PubMed entry. External link.

MARINDA ET, HARGROVE JW, PREISER W, SLABBERT JT, VAN ZYL GU, LEVIN J, MOULTON LH, WELTE A. Significantly diminished long-term specificity of the BED capture enzyme immunoassay among patients with HIV-1 with very low CD4 counts and those on antiretroviral therapy. Jaids-Journal of Acquired Immune Deficiency Syndromes 2009; 0 : 1-10.
No PubMed entry. External link.

PILLAY S, DE SWARDT D, KABUE J-P, GLASHOFF RH. TB co-infection is associated with increased cytotoxic phenotype marker expression in CD8+ T lymphocytes, but reduced HIV-specific degranulation. RETROVIROLOGY 2009; 6(3) : 249.
No PubMed entry. External link.

ROMANI B, ENGELBRECHT S, GLASHOFF RH. Antiviral roles of APOBEC proteins against HIV-1 and suppression by Vif. Archives of Virology 2009; 154 : 1579-1588.
PMID - 19669862

ROMANI B, ENGELBRECHT S. Human immunodeficiency virus type 1 Vpr: functions and molecular interactions. Journal of General Virology 2009; 90 : 1795-1805.
PMID - 19458171

ROMANI B, GLASHOFF RH, ENGELBRECHT S. Molecular and Phylogenetic Analysis of HIV Type 1 vpr Sequences of South African Strains. Aids Research and Human Retroviruses 2009; 25(3) : 1-6.
PMID - 19271970

VAN LOO KMJ, VAN SCHIJNDEL JE, VAN ZWEEDEN M, VAN MANEN D, TRIP MD, PETERSEN DC, SCHUITEMAKER H, HAYES V, MARTENS GJM. Correlation between HIV-1 seropositivity and prevalence of a y-Secretase polymorphism in two distinct ethnic populations. Journal of Medical Virology 2009; 81 : 1847-1851.
No PubMed entry. External link.

VAN ZYL GU, COTTON MF, CLAASSEN M, ABRAHAMS C, PREISER W. Surveillance of transmitted resistance to antiretroviral drug classes amongst young children in the Western Cape Province of South Africa. Pediatric Infectious Disease Journal 2009; 29 : 1-3.No PubMed entry. External link.

VAN ZYL GU, VAN DER MERWE L, CLAASSEN M, COTTON MF, RABIE H, PROZESKY HW, PREISER W. Protease inhibitor resistance in South African children with virologic failure. Pediatric Infectious Disease Journal 2009; 28(12) : 1-3.
PMID - 19779394

VAN ZYL GU. Susceptibility to serious viral disease in pregnancy - a problem of immune regulation?. Current Allergy & Clinical Immunology 2009; 22(4) : 166-167.
No PubMed entry. External link.

WILKINSON E, ENGELBRECHT S. Molecular characterization of non-subtype C and recombinant HIV-1 viruses from Cape Town, South Africa. Infection Genetics and Evolution 2009; 9 : 840-846.
PMID - 19446657

 

2008

Journal Articles

 

CLAASSEN M, VAN ZYL GU, PREISER W. Extraction buffer contaminated bacterially as a cause of invalid HIV-1 viral load results on the NucliSens EasyQ system. Journal of Virological Methods 2008; 150 : 80-81.
PMID - 18423634

ENGELBRECHT S, JACOBS GB, LOXTON AG, LATEN JD, ROBSON BA. Emergence and Diversity of Different HIV-1 Subtypes in Cape Town, South Africa. Aids Research and Human Retroviruses 2008; 24(1) : 159.
PMID - 19774685

HABTE HH, DE BEER C, LOTZ ZE, TYLER MG, KAHN D, MALL AS. Inhibition of Human Immunodeficiency virus Type 1 Activity by Purified Human Breast Milk Mucin (MUC1) in an Inhibition Assay. Neonatology 2008; 93 : 162-170.
PMID - 17878743

HABTE HH, DE BEER C, LOTZ ZE, TYLER MG, SCHOEMAN L, KAHN D, MALL AS. The inhibition of the Human Immunodeficiency virus type 1 activity by crude and purified human pregnancy plug mucus and mucins in an inhibition assay. VIROLOGY JOURNAL 2008; 5(59) : 1-10.
PMID - 18489743

JACOBS GB, LATEN JD, JANSE VAN RENSBURG E, BODERN J, WEISSBRICH B, RETHWILM A, PREISER W, ENGELBRECHT S. Phylogenetic Diversity and Low Level Antiretroviral Resistance Mutations in HIV Type 1 Treatment-Naive Patients from Cape Town, South Africa. Aids Research and Human Retroviruses 2008; 24(7) : 1-3.
PMID - 18593350

JACOBS GB, NISTAL M, LATEN JD, JANSE VAN RENSBURG E, RETHWILM A, PREISER W, BODERN J, ENGELBRECHT S. Molecular Analysis of HIV Type 1 vif Sequences from Cape Town, South Africa. Aids Research and Human Retroviruses 2008; 24(7) : 991-994.
PMID - 18593349

KOEHL U, DIRKWINKEL E, KOENIG M, ERBEN S, SOERENSEN J, BADER P, DOERR HW, PREISER W, WEISSINGER E, KLINGEBIEL T, MARTIN H, LEHRNBECHER T. Reconstitution of Cytomegalovirus Specific T Cells after Pediatric Allogeneic Stem Cell Transplantation: Results from a Pilot Study Using a Multi-Allele CMV Tetramer Group. Klinische Padiatrie 2008; 220 : 348-352.
PMID - 18949669

VAN ZYL GU, CLAASSEN M, ENGELBRECHT S, LATEN JD, COTTON MF, THERON GB, PREISER W. Zidovudine with nevirapine for the prevention of HIV mother-to-child transmission reduces nevirapine resistance in mothers from the Western Cape, South Africa. Journal of Medical Virology 2008; 80 : 942-946.
PMID - 18428139


2007

Journal Articles


HABTE HH, DE BEER C, LOTZ ZE, TYLER MG, KAN D, MALL AS. Inhibition of Human Immunodeficiency Virus Type 1 Activity by Purified Human Breast Milk Mucin (MUC1) in an Inhibition Assay. Neonatology 2007, 18, 93(3) : 162-170. 
PMID - 17878743

JACOBS GB, LOXTON AG, LATEN A, ENGELBRECHT S. Complete genome sequencing of a non-syncytium-inducing HIV type 1 subtype D strain from Cape Town, South Africa. AIDS Res Hum Retroviruses. 2007,23(12) : 1575-1578. 
PMID - 18160016

 

 

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