Mycobacteriology
Welcome to Stellenbosch University

Division of Molecular Biology & Human Genetics

Mycobacteriology​​​: Host-pathogen mycobactomics​

​Peer reviewed publications

2016

Mouton JM, Helaine S, Holden DW, Sampson SL. Elucidating population-wide mycobacterial replication dynamics at the single-cell level. Microbiology (2016). Accepted for publication

Newton-Foot M, Warren RM, Sampson SL, van Helden PD, Gey van Pittius NC. The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systems. BMC Evol Biol. 2016 16(1):62  

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Phelan JE, Coll F, Bergval I,  Anthony RM, Warren RM, Sampson SL and 24 other authors.  Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages.  BMC Genomics (2016). 17:151  

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Sampson SL. Strength in Diversity: Hidden Genetic Depths of Mycobacterium tuberculosis. Trends Microbiol. 2016 Jan 2. pii: S0966-842X(15)00297-8.                                                                             

 

2015

Black P, De Vos M, Louw G, Van der Merwe R,  Dippenaar A, Streicher E, Abdallah A, Sampson S,  Victor T, Dolby T, Simpson J, Van Helden P, Warren R, Pain A. Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates. BMC Genomics. 2015. 16(1):857

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Dippenaar A, Parsons SDC, Sampson SL, Van der Merwe RG, Drewe JA, Abdallah AM, Siame KK, Gey van Pittius NC, Van Helden PD, Pain A, Warren RM.  Whole genome sequence analysis of Mycobacterium suricattae. Tuberculosis. 2015. 95(6):682-8

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Pule C, Sampson SL (corresponding author), Warren RM, Black P, Van Helden PD, Victor TC, Louw GE. Efflux pump inhibitors: targeting mycobacterial efflux systems to enhance TB therapy. Journal of Antimicrobial Chemotherapy. 2015. 71(1):17-26

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Streicher EM, Sampson SL, Dheda K, Dolby T, Simpson J, Victor TC, Gey van Pittius NC, van Helden PD, Warren RM. Molecular epidemiological interpretation of the extensively drug resistant tuberculosis epidemic in South Africa J Clin Microbiol. 2015. 53(11):3650-3653

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Whitfield MG, Warren RM, Streicher EM, Sampson SL, Sirgel F, Van Helden PD, Mercante A, Willby M, Hughes K, Birkness K, Morlock G, Van Rie A, Posey J. Mycobacterium tuberculosis pncA polymorphisms that do not confer pyrazinamide resistance at a breakpoint concentration of 100 µg/ml in MGIT. J Clin Microbiol. 2015 53(11):3633-5

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Whitfield MG, Soeters HM, Warren RM, York T, Sampson SL, Streicher EM, van Helden PD, van Rie A. A Global Perspective on Pyrazinamide Resistance: Systematic Review and Meta-analysis. PLOS ONE. 2015 10(7):e0133869
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Fishbein S, Van Wyk N, Warren RM, Sampson SL. Phylogeny to function: PE/PPE protein evolution and impact on Mycobacterium tuberculosis pathogenicity. Molecular Microbiology. 2015.  doi: 10.1111/mmi.12981
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Fortuin S, Tomazella G, Nagayaryan N, Sampson S, Gey van Pittius N, Soares N, Wiker H, De Souza G, Warren R. Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: Expanding the mycobacterial phosphoproteome catalogue. Frontiers in Microbiology, section Microbial Physiology and Metabolism. 2015. doi: 10.3389/fmicb.2015.00006
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Fang Z, Sampson SL, Warren RM, Gey van Pittius NC, Newton-Foot M. Iron acquisition Strategies in Mycobacteria. Tuberculosis. 2015. 95(2):123-130
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2014

Van der Merwe RG, Van Helden PD, Warren RM, Sampson SLGey van Pittius NC. Phage-based detection of bacterial pathogens. Analyst2014 DOI: 10.1039/C4AN00208C
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Items in the press

What needs to be added to South Africa's anti-TB toolbox. SL Sampson. The Conversation, May 2015; http://theconversation.com/what-needs-to-be-added-to-south-africas-anti-tb-toolbox-40538 Republished under Creative Commons licence by: Biznews , The Big Issue, SciBraai

Fresh Hope for MDR-TB patients. SL Sampson. Sowetan. March 2014